2276-90-6 Usage
Description
Iothalamic acid, also known as Iothalamate, is an iodinated, water-soluble, off-white solid that belongs to the class of X-ray contrast agents. It is primarily used in diagnostic radiology to enhance the visualization of blood vessels, organs, and tissues during imaging procedures. Its chemical properties allow it to absorb X-rays, providing clear and detailed images for accurate diagnosis.
Uses
Used in Diagnostic Radiology:
Iothalamic acid is used as a contrast medium for various imaging techniques, such as angiography, urography, and computed tomography (CT) scans. It helps in improving the visualization of blood vessels, kidneys, and other internal structures, enabling doctors to detect abnormalities, assess organ function, and diagnose various medical conditions.
Iothalamic acid is used as a contrast medium for [application reason] in diagnostic radiology, where it enhances the visualization of blood vessels, organs, and tissues during imaging procedures.
Chemical Properties:
Iothalamic acid is an off-white solid with water-soluble properties, making it suitable for use as a contrast agent in medical imaging. Its iodine content allows it to absorb X-rays effectively, providing clear and detailed images for accurate diagnosis.
Safety and Nephroprotection:
Iothalamic acid has been found to display the same level of nephrotoxicity against rat and human renal epithelial cells as conventional ionic contrast media. This suggests that it may have similar safety profiles and potential risks associated with its use in diagnostic radiology. However, further research and clinical trials are necessary to fully understand its safety and efficacy in comparison to other contrast agents.
Therapeutic Function
Diagnostic aid (radiopaque medium)
Check Digit Verification of cas no
The CAS Registry Mumber 2276-90-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,2,7 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2276-90:
(6*2)+(5*2)+(4*7)+(3*6)+(2*9)+(1*0)=86
86 % 10 = 6
So 2276-90-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20)
2276-90-6Relevant articles and documents
Iodinated aroyloxy ketones
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, (2008/06/13)
Compounds having the structure STR1 wherein (Z--COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 20; R1, R2, R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, acylamino, acetamidoalkyl, acetamidoaryl, --COO-alkyl, --COO-aryl, --COO-aralkyl, --CO-alkyl, --CO-aryl, --CO-heterocyclyl, cyano or heterocyclyl; R5 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl, heterocyclyl, or a Z-CO2 -CR1 R2 (CR3 R4)n group, wherein Z, R1, R2, R3, R4 and n are as defined above, m is an integer from 0 to 10, p is an integer from 0 to 10, and m+p≥1 are useful as contrast agents in x-ray imaging compositions and methods.
Polyiodinated aroyloxy esters
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, (2008/06/13)
Compounds having the structure STR1 wherein Z--COO)m is the residue of a polyiodinated aromatic acid; m is 1, 2, 3 or 4; n is an integer from 1 to 20; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; and R5 is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; are useful as contrast agents in x-ray imaging compositions and methods.
Iodinated wetting agents
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, (2008/06/13)
Compounds having the structure STR1 wherein (Z)--COO is the residue of an iodinated aromatic acid; M is H, a cation, --CH2 CH2 O--m H, and --CH2 CH(OH)O--p H; m is an integer from 1 to 150; p is an integer from 1 to 50; and L is one or more divalent linking groups selected from alkylene, cycloalkylene, arylene, arylenealkylene, and alkylenearylene are particularly useful as wetting agents in x-ray imaging compositions.
