22795-97-7

Basic information

• Product Name: (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE
• Synonyms: (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE;(R)-2-(AMINOMETHYL)-1-ETHYLPYRROLIDINE;(R)-(+)-1-ETHYL-2-AMINOMETHYLPYRROLIDINE;S-(-)-N-Ethyl-2-aminomethylpyrrolidine;S-(-)2-(AminoMethyl)-N-EthylPyrrolidine;(R)-2-(AMINOMETHYL)-1-ETHYLPYRROLIDINE 98%;(R)-C-(1-Ethyl-pyrrolidin-2-yl)-methylamine;(R)-(1-ethylpyrrolidin-2-yl)methanamine
• CAS NO: 22795-97-7
• Molecular Formula: C₇H₁₆N₂
• Molecular Weight: 128.22
• Product Categories: Chiral Building Blocks;Heterocyclic Building Blocks;Pyrrolidines
• Mol File: 22795-97-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 50-52 °C(lit.)
• Flash Point: 57 °C
• Appearance: Clear colorless to yellow/Liquid
• Density: 0.90
• Refractive Index: 1.4655-1.4675
• Storage Temp.: 2-8°C
• PKA: 10.04±0.40(Predicted)
• Sensitive: Hygroscopic
• CAS DataBase Reference: (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE(22795-97-7)
• EPA Substance Registry System: (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE(22795-97-7)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 37/39-26-36-39-60-36/37/39-23
• RIDADR: UN 1993 3/PG 3
• WGK Germany: 2
• HazardClass: 8
• Hazardous Substances Data: 22795-97-7(Hazardous Substances Data)

Usage

Chemical Properties

Clear colorless to yellow liquid

InChI:InChI:1S/C7H16N2/c1-2-9-5-3-4-7(9)6-8/h7H,2-6,8H2,1H3

Upstream product

• 26116-12-1 1-ethyl-2-pyrrolidinemethanamine 

Downstream Products

• 72005-57-3 (R)-(+)-4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide L-tartrate 
• 1419752-11-6 (R)-4-(dimethylamino)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-nitrobenzamide 
• 1392138-96-3 C₂₃H₂₄FN₃O₂S 
• 1378379-82-8 4-chloro-N-(((R)-1-ethylpyrrolidin-2-yl)methyl)benzamide 
• 1378379-86-2 4-bromophenyl N-((R)-1-ethylpyrrolidin-2-yl)methylcarbamate 
• 1378379-85-1 N-(((R)-1-ethylpyrrolidin-2-yl)methyl)benzo[d]thiazole-6-carboxamide trifluoroacetate 
• 1097136-42-9 C₂₆H₂₃N₃O₂S 
• 1097136-24-7 C₂₆H₂₃N₃O₃ 
• 502767-56-8 N₂-cycloheptyl-N₄-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-N₆-(3-fluoro-4-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine 
• 502767-60-4 ({4-cycloheptylamino-6-[((R)-1-ethyl-pyrrolidin-2-ylmethyl)-amino]-1,3,5-triazin-2-yl}-phenyl-amino)-acetonitrile 
• 502767-58-0 N₂-cyclohexylmethyl-N₄-((R)-1-ethyl-pyrrolidin-2-ylmethyl)-N₆-(3-fluoro-4-methoxyphenyl)-1,3,5-triazine-2,4,6-triamine 
• 113531-33-2 (S)-N-<(1-Ethyl-2-pyrrolidinyl)methyl>-2,6-dimethoxybenzamide 
• 113452-78-1 N-((R)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide 
• 72442-43-4 4-Ethoxy-2-methyl-pyrimidine-5-carboxylic acid ((R)-1-ethyl-pyrrolidin-2-ylmethyl)-amide; compound with (E)-but-2-enedioic acid 

Relevant articles and documents

R-amisulpride medicine salt, preparation method, crystal form and application thereof

The invention concretely relates to R-amisulpride medicine salt, a preparation method, a crystal form and application thereof in preparing a medicine for treating diabetes. The preparation method comprises the following steps: by adopting 2-aminomethyl-N-ethyl pyrrolidine as a raw material, and adopting L-tartaric acid, for splitting to obtain (R)-2-aminomethyl-N-ethyl pyrrolidine; directly condensing amisulpride acid and the (R)-2-aminomethyl-N-ethyl pyrrolidine under the catalysis of isopropyl chlorocarbonate and triethylamine, thus obtaining R-amisulpride; reacting the R-amisulpride obtained in the step (2) and acid to obtain the R-amisulpride medicine salt. The preparation method has the advantages of simplicity in operation, high safety, good product quality, low cost and the like, and is convenient for scale production.