227959-99-1

Basic information

• Product Name: methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate
• Synonyms: methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate
• CAS NO: 227959-99-1
• Molecular Weight: 217.227
• Mol File: 227959-99-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate(227959-99-1)
• EPA Substance Registry System: methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate(227959-99-1)

Safety Data

• Hazardous Substances Data: 227959-99-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 64-18-6 formic acid 
• 634604-04-9 4-phenyl-1-(p-tolyl)-1H-1,2,3-triazole 
• 106-49-0 p-toluidine 
• 2101-86-2 p-methylazidobenzene 
• 292638-85-8 acrylic acid methyl ester 
• 1189781-14-3 C₈H₁₁N₃O₂ 
• 922-67-8 propynoic acid methyl ester 
• 90087-77-7 methyl 3-pyrrolidinoacrylate 

Downstream Products

• 227960-01-2 methyl N-(4-methylphenyl)ketenimine-2-carboxylate 
• 227960-12-5 methyl 5-methyl-1H-indole-3-carboxylate 
• 113934-31-9 1-(4-methylphenyl)-1H-[1,2,3]-triazol-4-yl carboxylic acid 

Relevant articles and documents

Design, synthesis and antibacterial evaluation of novel 15-membered 11a-azahomoclarithromycin derivatives with the 1, 2, 3-triazole side chain

Macrolides are widely prescribed in clinic to treat various respiratory tract infections. However, due to their inappropriate use, the prevalence of macrolide-resistant strains among clinical isolates has become a concern for public health. Therefore, nov

Copper Acetate Catalyzed Regio-selective Synthesis of Substituted 1,2,3-Triazoles: A Versatile Azide–Alk-ene Cycloaddition/Oxidation Approach

A copper acetate catalyzed oxidative cycloaddition reaction of benzyl and aryl azides with terminal and internal olefins that contain electron-withdrawing groups (COOR, CONH2, CN, CHO, COR) has been developed. The reaction employs air as the oxidant and does not require any base or additives to afford 1,4-disubstituted and 1,4,5-trisubstituted 1,2,3-triazoles in good to excellent yields with high regioselectivity.

Arylazide cycloaddition to methyl propiolate: DFT-based quantitative prediction of regioselectivity

Several 1-(4-substituted)-phenyl-4- or 5-methoxycarbonyl-1,2,3-triazoles have been synthesized by 1,3-dipolar cycloaddition of the corresponding arylazides to methyl propiolate in carbon tetrachloride. The regioselectivity of these reactions cannot be rat