22799-02-6

Basic information

• Product Name: 20-HYDROXYECDYSONE 22-ACETATE
• Synonyms: 2BETA,3BETA,14,20,22[R],25-HEXAHYDROXY-7-CHOLESTEN-6-ONE 22-ACETATE;20-HYDROXYECDYSONE 22-ACETATE;7-CHOLESTENE-2BETA,3BETA,14,20,22[R],25-HEXOL-6-ONE 22-ACETATE;7-Cholestene-2β,3β,14,20,22(R),25-hexol-6-one 22-acetate, 2β,3β,14,20,22(R),25-Hexahydroxy-7-cholesten-6-one 22-acetate;2β,3β,14,20,22(R),25-Hexahydroxy-7-cholesten-6-one 22-acetate;7-Cholestene-2β,3β,14,20,22(R),25-hexol-6-one 22-acetate
• CAS NO: 22799-02-6
• Molecular Formula: C₂₉H₄₆O₈
• Molecular Weight: 522.67
• Product Categories: Miscellaneous Natural Products
• Mol File: 22799-02-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 707.054°C at 760 mmHg
• Flash Point: 226.851°C
• Appearance: /
• Density: 1.266g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.58
• Storage Temp.: −20°C
• CAS DataBase Reference: 20-HYDROXYECDYSONE 22-ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 20-HYDROXYECDYSONE 22-ACETATE(22799-02-6)
• EPA Substance Registry System: 20-HYDROXYECDYSONE 22-ACETATE(22799-02-6)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 22799-02-6(Hazardous Substances Data)

Usage

Description

20-Hydroxyecdysone 22-Acetate is a naturally occurring ecdysteroid, a class of steroidal compounds found in plants and insects. It is known for its biological activity and potential applications in various fields, particularly in the development of steroidal ligands and gene switch modulation.

Uses

Used in Pharmaceutical Industry:
20-Hydroxyecdysone 22-Acetate is used as a precursor in the preparation of steroidal ligands for gene switch modulation. These ligands can be utilized to control gene expression, which has potential applications in the treatment of various diseases and conditions.
Additionally, 20-Hydroxyecdysone 22-Acetate has been studied for its potential use in the development of anabolic agents, anti-inflammatory drugs, and immune modulators due to its steroidal structure and biological activity. However, further research is needed to fully understand its potential applications and safety profile in these areas.

InChI:InChI=1/C29H46O8/c1-16(30)37-24(9-10-25(2,3)34)28(6,35)23-8-12-29(36)18-13-20(31)19-14-21(32)22(33)15-26(19,4)17(18)7-11-27(23,29)5/h13,17,19,21-24,32-36H,7-12,14-15H2,1-6H3/t17-,19-,21+,22-,23-,24+,26+,27+,28+,29+/m0/s1

Upstream product

• 84507-67-5 ecdysterone 2,3-monoacetonide 
• 5289-74-7 20-Hydroxyecdysone 
• 108-24-7 acetic anhydride 
• 169901-90-0 20-hydroxyecdysone 22-acetate 2,3-acetonide 

Downstream Products

• 128529-85-1 2-Deoxy-20-hydroxyecdysone-22-benzoate 
• 182422-98-6 C₃₅H₅₀O₁₀S 

Relevant articles and documents

Synthesis and biological activity of 2-deoxy-20-hydroxyecdysone and derivatives

The naturally occurring ecdysteroids 2-deoxy-20-hydroxyecdysone (2-D-20-ECD, 2-deoxycrustecdysone), 2-D-20-ECD 3-acetate (2-deoxyecdysterone 3-acetate), 2-D-20-ECD 22-acetate and 2-D-20-ECD 22-benzoate have been partially synthesized from 20-hydroxyecdysone. Moulting hormone activity of these ecdysteroids has been studied using the Musca bioassay.