22818-42-4Relevant articles and documents
A mild multistep conversion of n-protected α-amino acids into N-protected β3-amino acids utilizing the Nef reaction
Sleebs, Brad E.,Nguyen, Nghi H.,Hughes, Andrew B.
, p. 747 - 751 (2013/05/08)
Current methods of homologation of α-amino acids to β-amino acids have limitations. To overcome these shortfalls the Nef reaction has been utilized in the multistep synthesis of β3-amino acids from α-amino acids. In this approach, N-protected a
Ring-opening of N-tosyl aziridines by 2-lithiodithianes
Howson, William,Osborn, Helen M. I.,Sweeney, Joseph
, p. 2439 - 2446 (2007/10/02)
The reaction of lithiated dithianes 6-8 and 15 and 16 with enantiopure N-sulfonylated aziridines 1 and 2 leads via regiospecific nucleophilic ring-opening to enentiopure N-tosyl 2-(2'-dithianyl) secondary amines in good to excellent yields.These compounds
