22868-60-6

Basic information

• Product Name: 5-(1-piperidyl)furan-2-carbaldehyde
• Synonyms: 5-(1-piperidyl)furan-2-carbaldehyde;5-(1-PIPERIDINYL)-2-FURALDEHYDE;5-piperidin-1-yl-2-furaldehyde(SALTDATA: FREE);5-(1-piperidinyl)-2-Furancarboxaldehyde
• CAS NO: 22868-60-6
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.22
• Product Categories: Aldehydes;Furans, Benzofurans & Dihydrobenzofurans;Furans, Benzofurans & Dihydrobenzofurans
• Mol File: 22868-60-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 50.5-51.5 °C
• Boiling Point: 329.3°Cat760mmHg
• Flash Point: 153°C
• Appearance: /
• Density: 1.147g/cm³
• Vapor Pressure: 0.000179mmHg at 25°C
• Refractive Index: 1.554
• PKA: 1.57±0.20(Predicted)
• CAS DataBase Reference: 5-(1-piperidyl)furan-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(1-piperidyl)furan-2-carbaldehyde(22868-60-6)
• EPA Substance Registry System: 5-(1-piperidyl)furan-2-carbaldehyde(22868-60-6)

Safety Data

• Hazardous Substances Data: 22868-60-6(Hazardous Substances Data)

Usage

General Description

5-(1-piperidyl)furan-2-carbaldehyde, also known as NPC-16, is a chemical compound with a molecular formula C12H15NO2. It is a furan derivative with a piperidine substituent and a aldehyde functional group. It is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. This chemical is known to exhibit a variety of biological activities, including anti-inflammatory and antimicrobial properties. It has also been researched for its potential applications in the field of medicinal chemistry and drug development. Additionally, 5-(1-piperidyl)furan-2-carbaldehyde plays a role in the development of new materials and chemical products.

InChI:InChI=1/C10H13NO2/c12-8-9-4-5-10(13-9)11-6-2-1-3-7-11/h4-5,8H,1-3,6-7H2

Upstream product

• 110-89-4 piperidine 
• 1899-24-7 5-bromo-2-furancarboxaldehyde 
• 31795-44-5 5-formyl-2-furansulfonic acid sodium salt 
• 2689-65-8 5-iodofuran-2-carbaldehyde 

Downstream Products

• 84966-44-9 1-(3,5-Dinitrobenzoyloxy)-2-methyl-N-(5-piperidinofurfuryliden)-2-propanamin-N-oxid 
• 84966-55-2 <1-(Phenylcarbamoyloxy)cyclohexyl>-N-(5-piperidinofurfuryliden)methanamin-N-oxid 
• 84966-54-1 2-Methyl-1-(phenylcarbamoyloxy)-N-(5-piperidinofurfuryliden)-2-propanamin-N-oxid 
• 84966-21-2 2-Hydroxy-2-phenyl-N-(5-piperidinofurfuryliden)ethanamin-N-oxid 
• 84966-22-3 (1-Hydroxycyclohexyl)-N-(5-piperidinofurfuryliden)methanamin-N-oxid 
• 84966-45-0 1-Benzoyloxy-2-methyl-N-(5-piperidinofurfuryliden)-2-propanamin-N-oxid 

Relevant articles and documents

A facile preparation of trisubstituted amino-furan and -thiophene derivatives

β-Alkylation of amino-furan and -thiophene heterocycles is described through metal-, acid- and base-free carbon-carbon bond formation. The ability of both heterocycles to undergo selective β-alkylation is compared by mean of experimental and theoretical data. The presence of chiral amine substituents induced the diastereoselective generation of the newly formed additional stereocenter.

BCRP/ABCG2 INHIBITOR

The present invention is directed to a breast cancer resistance protein (BCRP/ABCG2) inhibitor. The BCRP inhibitor contains, as an active ingredient, an acrylonitrile derivative represented by formula (1): wherein one of R1 and R2 re

Ring-Chain Isomerism of N-(2-Hydroxyalkyl)nitrones, III. Nitrones of 2-Furancarbaldehydes

The ring-chain isomerism of N-(2-hydroxyalkyl)nitrones 3, obtained from 2-furancarbaldehyde and its 5-dialkylamino and 5-nitro derivatives, is studied by acylation of 3 with diphenylborinic acid, carboxylic acids, and isocyanates.Dependent on the kind of