229008-39-3

Basic information

• Product Name: 4-((N-3-hydroxypropyl-N-methyl)aminomethyl)-aniline
• Synonyms: 4-((N-3-hydroxypropyl-N-methyl)aminomethyl)-aniline
• CAS NO: 229008-39-3
• Molecular Weight: 194.277
• Mol File: 229008-39-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-((N-3-hydroxypropyl-N-methyl)aminomethyl)-aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((N-3-hydroxypropyl-N-methyl)aminomethyl)-aniline(229008-39-3)
• EPA Substance Registry System: 4-((N-3-hydroxypropyl-N-methyl)aminomethyl)-aniline(229008-39-3)

Safety Data

• Hazardous Substances Data: 229008-39-3(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 555-16-8 4-nitrobenzaldehdye 
• 56553-60-7 sodium tris(acetoxy)borohydride 
• 156-87-6 propan-1-ol-3-amine 
• 229008-38-2 3-[methyl-(4-nitro-benzyl)-amino]-propan-1-ol 
• 1038231-31-0 3-((4-nitrobenzyl)amino)propan-1-ol 

Downstream Products

• 229005-67-8 N-(4-((N-3-hydroxypropyl-N-methyl)aminomethyl)phenyl)-7-(4-methylphenyl)-2,3-dihydro-1-benzoxepine-4-carboxamide 
• 229005-94-1 N-(4-((N-3-hydroxypropyl-N-methyl)aminomethyl)phenyl)-7-(4-methylphenyl)-2,3-dihydro-1-benzothiepine-4-carboxamide 
• 229005-66-7 N-(4-((N-3-hydroxypropyl-N-methyl)aminomethyl)phenyl)-2-(4-methylphenyl)-6,7-dihydro-5H-benzocycloheptene-8-carboxamide 

Relevant articles and documents

Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: Synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety

The search for new small-molecule CCR5 antagonists by high-throughput screening (HTS) of the Takeda chemical library using [125I]RANTES and CHO/CCR5 cells led to the discovery of lead compounds (A, B) with a quaternary ammonium or phosphonium m

Anilide derivative, production and use thereof

This invention is to provide a compound of the formula: wherein R1 is an optionally substituted 5- to 6-membered ring: C is a divalent group of the formula: wherein the ring A is an optionally substituted 5- to 6-membered aromatic ring, X is an optionally substituted C, N or O atom, and the ring B is an optionally substituted 5- to 7-membered ring; Z is a chemical bond or a divalent group; R2 is (1) an optionally substituted amino group in which a nitrogen atom may form a quaternary ammonium, etc., or a salt thereof, which is useful for antagonizing MCP-1 receptor.