229153-21-3 Usage
General Description
2',4'-difluoro-α-(ethylthio)acetophenone is a chemical compound with the molecular formula C10H9F2OS. It is a white or off-white solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 2',4'-difluoro-α-(ethylthio)acetophenone contains a fluoro-substituted phenyl ring attached to a ketone group and an ethylthio side chain. It is a versatile building block for the preparation of diverse chemical compounds due to its reactivity and substituent pattern. Additionally, 2',4'-difluoro-α-(ethylthio)acetophenone is also used as a flavoring agent in the food industry. However, it is important to handle this chemical with caution as it can be harmful if ingested or inhaled and can also cause skin and eye irritation.
Check Digit Verification of cas no
The CAS Registry Mumber 229153-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,9,1,5 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 229153-21:
(8*2)+(7*2)+(6*9)+(5*1)+(4*5)+(3*3)+(2*2)+(1*1)=123
123 % 10 = 3
So 229153-21-3 is a valid CAS Registry Number.
229153-21-3Relevant articles and documents
α, α-gem-difluorination of α-(alkylthio)acetophenone derivatives with N-Fluoropyridinium salts
Takeda, Sunao,Kaneko, Yasushi,Eto, Hiromichi,Tokizawa, Minoru,Sato, Susumu,Yoshida, Kouiti,Namiki, Setsuo,Ogawa, Masaki
, p. 1097 - 1100 (2000)
The α, α-gem-difluorination of 2',4'-difluoro- α(methylthio)acetophenone (1a) with N-fluoropyridinium salts gave 2',4',α-tetrafluoro-α-(methylthio)acetophenone (3a). This reaction was accelerated by the addition of zinc chloride, zinc bromide or anhydrous iron(III) chloride, and higher yields than the reaction without additives were obtained. The gem- difluorination reaction using FP-T300 in the presence of zinc bromide was applicable to other α-(alkylthio)acetophenone derivatives (1).
