22963-71-9

Basic information

• Product Name: 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI-
• Synonyms: 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI-
• CAS NO: 22963-71-9
• Molecular Formula: C9H17NO2.ClH
• Molecular Weight: 207.699
• Product Categories: ESR Reagents;Analytical/Chromatography;Spectroscopy
• Mol File: 22963-71-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 170-174 °C (dec.)
• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI-(22963-71-9)
• EPA Substance Registry System: 1-HYDROXY-2 2 6 6-TETRAMETHYL-4-PIPERI-(22963-71-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 22963-71-9(Hazardous Substances Data)

Usage

Chemical structure

1-Hydroxy-2,2,6,6-tetramethyl-4-piperidinyl-1-oxyl

Type of compound

Hydroxy derivative of 2,2,6,6-tetramethylpiperidine

Stability

Stable free radical

Antioxidant properties

Powerful antioxidant

Function

Scavenges free radicals and protects cells from oxidative damage

Potential therapeutic applications

Treatment of diseases and conditions related to oxidative stress

Potential industrial applications

Development of new materials with antioxidant properties

Current status

Used in laboratory research and scientific experimentation

Further research needed

To fully understand the potential benefits and applications in the field of chemistry and biomedicine.

Upstream product

• 45985-26-0 4-oxo-2,2,6,6-tetramethylpiperidin-oxyl 

Downstream Products

• 45985-26-0 4-oxo-2,2,6,6-tetramethylpiperidin-oxyl 
• 113682-53-4 1-acetoxy-2,2,6,6-tetramethyl-4-piperidone 

Relevant articles and documents

Synthesis of poly(vinyl acetate) and poly(vinyl alcohol) containing block copolymers by combination of cobalt-mediated radical polymerization and ATRP

Poly(vinyl acetate) (PVAc) chains of a low polydispersity (M w/Mn ~ 1.1-1.2) have been prepared by cobalt-mediated radical polymerization of vinyl acetate (VAc). They have been end-capped by an activated bromide by addition of an α-bromoester or an a-bromoketone containing nitroxide and converted into effective macroinitiators for the atom transfer radical polymerization of styrene (Sty), ethyl acrylate, and methyl methacrylate. Because each block is formed by a controlled process, well-defined PVAc containing diblock copolymers are easily prepared. The PVAc-b-PS copolymers synthesized from α-bromoketone end-capped PVAc can be converted into well-defined poly(vinyl alcohol)-b-polystyrene amphiphiles by methanolysis of the poly(vinyl acetate) block. Self-association of an amphiphilic poly(vinyl alcohol)(3500)-b-polystyrene(16 600) in a (4/1) water/tetrahydrofuran mixture results in the formation of vesicles as observed by transmission electron microscopy.

HYDROXYLAMINE COMPOUNDS AND METHODS OF THEIR USE

The present disclosure provides compounds that include hydroxylamines of formula (I) or (II), pharmaceutical compositions, and methods for their use. The methods utilize hydroxylamine compounds and/or their pharmaceutical compositions for the treatment of angiogenesis, hepatitis, complement-mediated pathologies, drusen-mediated pathologies, macular degeneration and certain other ophthalmic conditions, inflammation, arthritis, and related diseases and for the inhibition of complement activation.

A Study of the Favorskii Rearrangement with 3-Bromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-oxyl

Favorskii rearrangement reactions of the title compound with sodium hydroxide, sodium ethoxide, ammonia, several aliphatic amines, and ethyl sodiomalonate resulting in pyrrolidine nitroxyl radicals are described.