22965-93-1

Basic information

• Product Name: (Z)-2-Bromo-1-phenyl-2-butyn-1-one
• Synonyms: (Z)-2-Bromo-1-phenyl-2-butyn-1-one
• CAS NO: 22965-93-1
• Molecular Weight: 225.085
• Mol File: 22965-93-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-2-Bromo-1-phenyl-2-butyn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Bromo-1-phenyl-2-butyn-1-one(22965-93-1)
• EPA Substance Registry System: (Z)-2-Bromo-1-phenyl-2-butyn-1-one(22965-93-1)

Safety Data

• Hazardous Substances Data: 22965-93-1(Hazardous Substances Data)

Upstream product

• 90798-46-2 2,3-dibromo-1-phenyl-1-butanone 
• 52755-39-2 (2E)-1-phenylbut-2-en-1-ol 
• 100-58-3 phenylmagnesium bromide 
• 622-76-4 1-phenyl-1-butyne 
• 591-50-4 iodobenzene 
• 73922-81-3 4-phenyl-but-3-yn-2-ol 
• 5405-34-5 (Z)-2-bromobut-2-enoic acid 
• 71-43-2 benzene 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 

Downstream Products

• 1008-74-8 5-methyl-3-phenylisoxazole 
• 1008-75-9 3-methyl-5-phenylisoxazole 

Relevant articles and documents

Modular access to 1,2-allenyl ketones based on a photoredox-catalysed radical-polar crossover process

Herein, a new protocol dealing with the preparation of 1,2-allenyl ketones has been successfully developedviathe reactions of enynes with radicals enabled by dual photoredox/copper catalysis. Based on the results of a deuteration experiment and the competition reaction between cyclopropanation and allenation, the mechanism based on a photoredox-neutral-catalysed radical-polar crossover process has been proposed. Synthetic applications of allenes have also been demonstrated.

α-Haloenones from secondary alkynols

α-Iodoenones and α-bromoenones are formed from secondary alkynols by the use of the appropriate N-halosuccinimide and a catalytic amount of certain Lewis acids. For example, 3-hexyn-2-ol (1) was converted to (Z)-4-iodo-4-hexen-3-one (2) in 85-95% yields w