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22972-63-0

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22972-63-0 Usage

General Description

2-(3,5-DIMETHOXY-PHENYL)-2-METHYL-PROPIONITRILE, also known as DMPN, is a chemical compound with the molecular formula C12H15NO3. It is a nitrile derivative that is used in the synthesis of pharmaceuticals and agrochemicals. DMPN is a white crystalline solid with a slightly fruity odor, and it is soluble in organic solvents such as acetone and ethanol. It has been identified as an intermediate in the production of various pharmaceutical compounds, and it is also used as a building block in the synthesis of other organic compounds. DMPN has been studied for its potential pharmacological activities, including its antifungal and antimicrobial properties. However, it should be handled with care as it may cause skin and eye irritation, and it should be used only under controlled conditions to prevent exposure and potential health risks.

Check Digit Verification of cas no

The CAS Registry Mumber 22972-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,9,7 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22972-63:
(7*2)+(6*2)+(5*9)+(4*7)+(3*2)+(2*6)+(1*3)=120
120 % 10 = 0
So 22972-63-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO2/c1-12(2,8-13)9-5-10(14-3)7-11(6-9)15-4/h5-7H,1-4H3

22972-63-0Relevant articles and documents

Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists

Jiang, Shan,Iliopoulos-Tsoutsouvas, Christos,Tong, Fei,Brust, Christina A.,Keenan, Catherine M.,Raghav, Jimit Girish,Hua, Tian,Wu, Simiao,Ho, Jo-Hao,Wu, Yiran,Grim, Travis W.,Zvonok, Nikolai,Thakur, Ganesh A.,Liu, Zhi-Jie,Sharkey, Keith A.,Bohn, Laura M.,Nikas, Spyros P.,Makriyannis, Alexandros

, p. 3870 - 3884 (2021/05/04)

We report the development of novel cannabinergic probes that can stabilize the cannabinoid receptors (CBRs) through tight binding interactions. Ligand design involves the introduction of select groups at a judiciously chosen position within the classical

CANNABINOIDS AND USES THEREOF

-

Page/Page column 82-83, (2019/12/25)

The invention relates to cannabinoid compounds, pharmaceutical compositions including one or more cannabinoid compounds, and the use of pharmaceutical compositions including one or more cannabinoid compounds for the treatment of a disease or condition (e.

Synthesis, radio-synthesis and in vitro evaluation of terminally fluorinated derivatives of HU-210 and HU-211 as novel candidate PET tracers

Zanato, Chiara,Pelagalli, Alessia,Marwick, Katie F. M.,Piras, Monica,Dall'Angelo, Sergio,Spinaci, Andrea,Pertwee, Roger G.,Wyllie, David J. A.,Hardingham, Giles E.,Zanda, Matteo

, p. 2086 - 2096 (2017/03/11)

We report the synthesis of terminally fluorinated HU-210 and HU-211 analogues (HU-210F and HU-211F, respectively) and their biological evaluation as ligands of cannabinoid receptors (CB1 and CB2) and N-methyl d-aspartate receptor (NMDAR). [18F]-labelled HU-210F was radiosynthesised from the bromo-substituted precursor. In vitro assays showed that both HU-210F and HU-211F retain the potent pharmacological profile of HU-210 and HU-211, suggesting that [18F]-radiolabelled HU-210F and HU-211F could have potential as PET tracers for in vivo imaging.

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