2305-85-3 Usage
Description
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is a heterocyclic chemical compound with the molecular formula C9H10N2. It belongs to the quinazoline class of organic compounds and is recognized for its role as a precursor in the synthesis of various pharmaceutical drugs. 2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) has demonstrated a range of pharmacological properties, such as antiviral, antifungal, and anticancer activities, along with potential applications in the treatment of neurological and psychiatric disorders. Its ability to modulate the activity of certain enzymes and receptors makes it a valuable compound in medicinal chemistry research for the development of new drug candidates and therapeutic agents.
Uses
Used in Pharmaceutical Industry:
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is used as a precursor in the synthesis of pharmaceutical drugs for its diverse pharmacological properties. It serves as a key intermediate in the development of new drug candidates with potential applications in treating various diseases and conditions.
Used in Antiviral Applications:
In the field of antiviral research, 2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is utilized for its antiviral properties, contributing to the development of drugs that can combat viral infections effectively.
Used in Antifungal Applications:
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is also employed in antifungal applications, where it is used to develop drugs that target and eliminate fungal infections, providing a therapeutic solution for various fungal-related conditions.
Used in Anticancer Applications:
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is used in the development of anticancer drugs, leveraging its potential to inhibit the growth and proliferation of cancer cells, thus offering a promising avenue for cancer treatment.
Used in Neurological and Psychiatric Disorders Treatment:
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) has been studied for its potential use in the treatment of neurological and psychiatric disorders, where it may help modulate the activity of certain enzymes and receptors, contributing to the development of therapeutic agents for these conditions.
Used in Enzyme and Receptor Modulation:
2-Quinazolinamine, 5,6,7,8-tetrahydro(9CI) is utilized in research for its ability to modulate the activity of enzymes and receptors in the body, which can be instrumental in the development of drugs targeting specific biological pathways and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 2305-85-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,0 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2305-85:
(6*2)+(5*3)+(4*0)+(3*5)+(2*8)+(1*5)=63
63 % 10 = 3
So 2305-85-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3/c9-8-10-5-6-3-1-2-4-7(6)11-8/h5H,1-4H2,(H2,9,10,11)
2305-85-3Relevant articles and documents
Efficient synthesis of 4- And 5-substituted 2-aminopyrimidines by coupling of β-Chlorovinyl Aldehydes and Guanidines
Komendantova, Anna S.,Komkov, Alexander V.,Volkova, Yulia A.,Zavarzin, Igor V.
, p. 4247 - 4254 (2018/08/24)
A general, practical, and simple synthesis of functionalized 2-aminopyrimidines starting from β-chlorovinyl aldehydes and amidines is reported. In the presence of potassium carbonate, various ketones have been efficiently transformed into the pyrimidine derivatives by a two-step sequence involving the Vilsmeier-Haack reaction followed by a condensation reaction with guanidines. The protocol is distinguished by operational simplicity, inexpensive reagents, and functional-group tolerance. In many cases, pure solid products can be obtained in high to excellent yields without using column chromatography. The synthetic value of the method was demonstrated by the efficient synthesis of steroidal pyrimidines and a precursor of the antitumor agents Imatinib and Mocetinostat.
2-Aminopyrimidines in just two steps from ketones, acetylenes and guanidine via β,γ enones
Schmidt, Elena Yu.,Tatarinova, Inna V.,Ivanova, Elena V.,Trofimov, Boris A.
, p. 283 - 284 (2017/06/06)
Available β,γ-enones, the products of nucleophilic addition of ketones to phenylacetylene, react with guanidine in the KOH / DMSO system at 70?°C to give 2-aminopyrimidines in up to 72% yield.
On tetrodotoxin.VI. 2-Amino-6-methylquinazoline as decomposition products of tetrodotoxin.
TSUDA,IKUMA,KAWAMURA,TACHIKAWA,MIYADERA
, p. 868 - 870 (2007/10/04)
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