23052-80-4 Usage
Description
L-AP3, also known as L-2-amino-3-phosphonopropionic acid, is a synthetic compound that acts as a selective antagonist of the PI-linked metabotropic glutamate response. It is a white crystalline powder with unique chemical properties that make it valuable in various applications.
Uses
Used in Pharmaceutical Industry:
L-AP3 is used as a pharmaceutical compound for its ability to selectively antagonize the PI-linked metabotropic glutamate response. This property makes it a valuable tool in the development of drugs targeting neurological disorders and conditions related to glutamate signaling.
Used in Research and Development:
In the field of research and development, L-AP3 is used as a research chemical to study the role of metabotropic glutamate receptors in various biological processes. Its selective antagonistic action helps scientists understand the underlying mechanisms of these receptors and their potential therapeutic applications.
Used in Neurological Disorder Treatment:
L-AP3 is used as a potential therapeutic agent for the treatment of neurological disorders that involve the dysregulation of glutamate signaling, such as epilepsy, Alzheimer's disease, and Parkinson's disease. Its ability to selectively target the PI-linked metabotropic glutamate response makes it a promising candidate for the development of novel treatments for these conditions.
Biochem/physiol Actions
Potent antagonist at metabotropic glutamic acid receptors.
Check Digit Verification of cas no
The CAS Registry Mumber 23052-80-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,0,5 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 23052-80:
(7*2)+(6*3)+(5*0)+(4*5)+(3*2)+(2*8)+(1*0)=74
74 % 10 = 4
So 23052-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C3H8NO5P/c4-2(3(5)6)1-10(7,8)9/h2H,1,4H2,(H,5,6)(H2,7,8,9)/p-2/t2-/m0/s1
23052-80-4Relevant articles and documents
PREPARATION D'ACIDES AMINOCARBOXY-ALKYLPHOSPHONIQUES OPTIQUEMENT ACTIFS
Villanueva, J. M.,Collignon, N.,Guy, A.,Savignac, Ph.
, p. 1299 - 1306 (2007/10/02)
In aqueous solution ω-formylalkylphosphonates in the presence of hydrogen cyanide and (S) (-) α-methylbenzylamine give optically active aminonitriles with an enantiomeric excess of 50percent.Phosphonic aminonitriles are submitted to acid hydrolysis, then esterified and debenzylated without any epimerization.The separation is performed either with the acid or with the ester.All the operations are monitored by NMR (1H, 13C, 31P) and whenever possible, by GC.
