230642-77-0

Basic information

• Product Name: trans-3,5-dichlorocinnamic acid tert-butyl ester
• Synonyms: trans-3,5-dichlorocinnamic acid tert-butyl ester
• CAS NO: 230642-77-0
• Molecular Weight: 273.159
• Mol File: 230642-77-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: trans-3,5-dichlorocinnamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: trans-3,5-dichlorocinnamic acid tert-butyl ester(230642-77-0)
• EPA Substance Registry System: trans-3,5-dichlorocinnamic acid tert-butyl ester(230642-77-0)

Safety Data

• Hazardous Substances Data: 230642-77-0(Hazardous Substances Data)

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 39943-56-1 3,5-dichlorophenylhydrazine 
• 10203-08-4 3,5-dichlorobenzaldehyde 
• 27784-76-5 tert-butyl diethylphosphonoacetate 

Relevant articles and documents

Palladium-catalyzed C-C bond formation of arylhydrazines with olefins via carbon-nitrogen bond cleavage

The unactivated carbon-nitrogen bond of various aryl hydrazines was cleaved under very mild conditions by Pd(0) with the assistance of Pd(II). The in situ generated aryl palladium complex readily takes part in the C-C bond formation with olefins. This study offered a new mode of C-Pd bond formation, which will spur the development of palladium-catalyzed cross-coupling in the future.

Heterocyclic sodium/proton exchange inhibitors and method

Heterocyclic are provided which are sodium/proton exchange (NHE) inhibitors which have the structure wherein n is 1 to 5; X is N or C—R5 wherein R5 is H, halo, alkenyl, alkynyl, alkoxy, alkyl, aryl or heteroaryl; Z is a heteroaryl gorup, R1, R2, R3 and R4 are as defined herein, and where X is N. R1 is preferably aryl or heteroaryl, and are useful as antianginal and cardioprotective agents. In addition, a method is provided for preventing or treating angina pectoris, cardiac dysfunction, myocardial necrosis, and arrhythmia employing the above heterocyclic derivatives.