2316-61-2

Basic information

• Product Name: 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL
• Synonyms: 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL;5-BROMO-4-HYDROXY-3-METHOXYBENZYL ALCOHOL;RARECHEM AL BD 0099;3-Bromo-4-hydroxy-5-methoxybenzyl alcohol, 3-Bromo-2-hydroxy-5-(hydroxymethyl)anisole;3-BROMO-4-HYDROXY-5-METHOXYBENZYL ALCOHOL
• CAS NO: 2316-61-2
• Molecular Formula: C₈H₉BrO₃
• Molecular Weight: 233.06
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 2316-61-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 132 °C
• Boiling Point: 326.7±37.0 °C(Predicted)
• Appearance: /
• Density: 1.642±0.06 g/cm3(Predicted)
• PKA: 8.23±0.23(Predicted)
• CAS DataBase Reference: 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL(2316-61-2)
• EPA Substance Registry System: 2-BROMO-4-(HYDROXYMETHYL)-6-METHOXYPHENOL(2316-61-2)

Safety Data

• Hazardous Substances Data: 2316-61-2(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 

Relevant articles and documents

Approach to Merosesquiterpenes via Lewis Acid Catalyzed Nazarov-Type Cyclization: Total Synthesis of Akaol A

A Lewis acid catalyzed Nazarov-type cyclization of arylvinylcarbinol has been developed for the asymmetric synthesis of carbotetracyclic core of merosesquiterpenes. The reaction works only in the presence of 2 mol % of Sn(OTf)2 and Bi(OTf)3 in dichloroethane under elevated temperature. The methodology offers the synthesis of a variety of enantioenriched arylvinylcarbinols from commercially available (3aR)-sclareolide 9 in six steps with an eventual concise total synthesis of marine sesquiterpene quinol, akaol A (1a).

HIV INTEGRASE INHIBITORY OXOISOINDOLINE SULFONAMIDES

Novel oxoisoindoline sulfonamide integrase inhibitors are useful to inhibit HIV activity, and are therefore suitable for treatment or prophylaxis of HIV infection, for example in the treatment or prevention of AIDS. In particular embodiments, the inhibito

A cascade cyclization approach to schweinfurthin B

(graph presented) A strategy for synthesis of the hexahydroxanthene moiety of the natural products schweinfurthin A, B, and D is described. The relative stereochemistry in the key cationic cyclization step is established through the preference of the phen