23226-10-0

Basic information

• Product Name: 3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one
• Synonyms: 3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one
• CAS NO: 23226-10-0
• Molecular Weight: 299.372
• Mol File: 23226-10-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one(23226-10-0)
• EPA Substance Registry System: 3-benzyl-1,3-dihydro-1-phenyl-2H-indol-2-one(23226-10-0)

Safety Data

• Hazardous Substances Data: 23226-10-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 1075174-08-1 (E)-3-benzylidene-1-phenylindolin-2-one 
• 3335-98-6 1-phenyl-1,3-dihydro-indol-2-one 
• 100-51-6 benzyl alcohol 

Downstream Products

• 1372925-44-4 C₃₁H₂₁F₆NO₃ 
• 1372925-77-3 C₃₈H₂₇F₆NO₄ 
• 1290607-19-0 N-((S)-1-((R)-3-benzyl-2-oxo-1-phenylindolin3-yl)-2-nitroethyl)acetamide 

Relevant articles and documents

The Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed Reductions of α, β-Unsaturated Carbonyl Compounds

Sodium hydride was employed as a Michael donor under the catalysis of PdCl2 for 1,4-conjugate reductions of α, β-unsaturated carbonyl compounds, which features operational simplicity, mild conditions and high atom-economy. The merits of NaH as a reductant were demonstrated by the one-pot or cascade reactions for the syntheses of complex molecules. (Figure presented.).

Application of metal hydride/palladium compound catalytic reduction system in alkenyl active methylene compound reduction and reduction method

The invention discloses application of a metal hydride/palladium compound catalytic reduction system in alkenyl active methylene compound reduction and a reduction method. Reaction comprises the following steps that an alkenyl active methylene compound is

C-3 alkylation of oxindole with alcohols by Pt/CeO2 catalyst in additive-free conditions

In a series of transition metal-loaded CeO2 catalysts and Pt-loaded catalysts on various supports, Pt-loaded CeO2 shows the highest activity for the selective C-3 alkylation of oxindole with octanol. The catalyst is effective for alkylation of oxindole and N-substituted oxindole with a series of substituted benzyl, linear, hetero-aryl alcohols under additive-free conditions and is recyclable. Our results demonstrate the first additive-free catalytic system for this reaction. Mechanistic studies show that this system is driven by the borrowing-hydrogen pathway. Structure-activity relationship studies show that co-presence of surface Pt0 species on Pt metal clusters and basic support is indispensable for this catalytic system. This journal is the Partner Organisations 2014.