23246-96-0 Usage
Description
Riddelline is a macrolide that is 13,19-didehydrosenecionan bearing two additional hydroxy substituents at positions 12 and 18, as well as two additional oxo groups at positions 11 and 16. It is a colorless to off-white crystalline solid that starts turning brown at approximately 329°F and turns blackish-brown at its melting point.
Uses
Used in Medicinal Herb Preparations:
Riddelliine is used in medicinal herb preparations, particularly from the plant Senecio longilobus in the United States. Additionally, other riddelliine-containing plants such as S. jacobaea and S. vulgaris are used in medicinal preparations in other parts of the world for their potential therapeutic properties. However, riddelliine and riddelliine N-oxide have no known commercial uses, and riddelliine-containing plants are not used for food in the United States.
Air & Water Reactions
Exposure to light and air can cause gradual oxidation. Insoluble in water.
Reactivity Profile
riddelline reacts readily with oxidizing agents (slowly with atmospheric oxygen). On contact with bases, hydrolysis will probably occur .
Fire Hazard
Flash point data for riddelline are not available; however, riddelline is probably combustible.
Potential Exposure
Riddelline is a natural alkaloid product
used a laboratory chemical and reference standard.
Carcinogenicity
Riddelliine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting data from studies on mechanisms of carcinogenesis.
Shipping
UN1544 Alkaloids, solid, n.o.s. or Alkaloid salts,
solid, n.o.s. poisonous, Hazard Class: 6.1; Labels:
6.1-Poisonous materials, Technical Name Required.
Incompatibilities
Riddelline is sensitive to light, air, and
heat, causing oxidation; reacts slowly with atmospheric
oxygen. This chemical is probably combustible; dust mixed with air may be explosive. Incompatible with oxidizers
(chlorates, nitrates, peroxides, permanganates, perchlorates,
chlorine, bromine, fluorine, etc.); contact may cause fires
or explosions. Keep away from alkaline materials, strong
bases, strong acids, oxoacids, and epoxides. Contact with
alkalis and bases may cause hydrolysis.
Waste Disposal
It is inappropriate and possi-
bly dangerous to the environment to dispose of expired or
waste product such as lab chemicals by flushing them
down the toilet or discarding them to the trash. Larger
quantities shall carefully take into consideration applicable
EPA, and FDA regulations. If possible return the lab che-
micals to the manufacturer for proper disposal being careful
to properly label and securely package the material.
Alternatively, the waste lab chemicals shall be labeled,
securely packaged and transported by a state licensed medi-
cal waste contractor to dispose by burial in a licensed haz-
ardous or toxic waste landfill or incinerator.
Check Digit Verification of cas no
The CAS Registry Mumber 23246-96-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,2,4 and 6 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 23246-96:
(7*2)+(6*3)+(5*2)+(4*4)+(3*6)+(2*9)+(1*6)=100
100 % 10 = 0
So 23246-96-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H23NO6/c1-3-12-8-11(2)18(23,10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4,14-15,20,23H,2,5-10H2,1H3/b12-3-/t14-,15-,18-/m1/s1