233272-33-8Relevant articles and documents
Synthesis of Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (5-GTIC, 6-GTIC and 8-GTIC)
Severino, Beatrice,Santagada, Vincenzo,Frecentese, Francesco,Perissutti, Elisa,Terracciano, Sara,Fiorino, Ferdinande,Cirillo, Donatella,Salvadori, Severo,Balboni, Gianfranco,Caliendo, Giuseppe
, p. 3011 - 3016 (2004)
Nα-Fmoc N,N′-bis-Boc-5-, 6- and 8-guanyl-Tic-OH (5-, 6- and 8-GTIC), three conformationally constrained amino acids with basic properties, have been synthesized by microwave irradiation. These amino acids combine the basic features of arginine with the aromatic features of phenylalanine and can be utilized as functional tools in peptide-based structure-activity studies.