23350-02-9

Basic information

• Product Name: 4-Isoxazolamine,3-phenyl-(9CI)
• Synonyms: 4-Isoxazolamine,3-phenyl-(9CI);3-Phenylisoxazol-4-amine;3-Phenyl-isoxazol-4-ylamine
• CAS NO: 23350-02-9
• Molecular Formula: C₉H₈N₂O
• Molecular Weight: 160.17
• Product Categories: OXAZOLE
• Mol File: 23350-02-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Isoxazolamine,3-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Isoxazolamine,3-phenyl-(9CI)(23350-02-9)
• EPA Substance Registry System: 4-Isoxazolamine,3-phenyl-(9CI)(23350-02-9)

Safety Data

• Hazardous Substances Data: 23350-02-9(Hazardous Substances Data)

Upstream product

• 65651-80-1 ethyl (E)-3-(pyrrolidin-1-yl)acrylate 
• 698-16-8 benzohydroximoyl chloride 
• 104-55-2 3-phenyl-propenal 
• 31301-41-4 4-nitro-3-phenylisoxazole 

Downstream Products

• 53289-83-1 (5-nitro-furan-2-ylmethylene)-(3-phenyl-isoxazol-4-yl)-amine 

Relevant articles and documents

Synthesis of 4-amino-5-allenylisoxazolesviagold(i)-catalysed propargyl aza-Claisen rearrangement

Propargyl aza-Claisen rearrangement of 4-propargylaminoisoxazoles1proceeded in the presence of cationic gold(i) catalysts to give 4-amino-5-allenylisoxazoles2in good to high yields. The silyl group at the terminal alkyne and a cationic gold(i) catalyst bearing a sterically bulky ligand are essential for the generation of isolable allene intermediates. TheN-protection of the generated 4-amino-5-allenylisoxazoles2allowed the isolation of 5-allenylisoxazoles4that have never been synthesized.N-Propargyl aniline5was successfully converted to the correspondingortho-allenyl aniline6under the current reaction conditions.