23354-30-5

Basic information

• Product Name: 3-BROMO-5-HYDROXY-4-METHOXYBENZALDEHYDE
• Synonyms: 3-BROMO-5-HYDROXY-4-METHOXYBENZALDEHYDE;3-bromo-4-methoxy-5-hydroxybenzaldehyde
• CAS NO: 23354-30-5
• Molecular Formula: C₈H₇BrO₃
• Molecular Weight: 231.04
• Mol File: 23354-30-5.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BROMO-5-HYDROXY-4-METHOXYBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-HYDROXY-4-METHOXYBENZALDEHYDE(23354-30-5)
• EPA Substance Registry System: 3-BROMO-5-HYDROXY-4-METHOXYBENZALDEHYDE(23354-30-5)

Safety Data

• Hazardous Substances Data: 23354-30-5(Hazardous Substances Data)

Upstream product

• 80547-72-4 acetic acid 5-formyl-2-methoxy-3-nitrophenyl ester 
• 186581-53-3 diazomethane 
• 16414-34-9 3-bromo-4,5-dihydroxybenzaldehyde 
• 74-88-4 methyl iodide 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 121-33-5 vanillin 
• 2973-76-4 5-bromo-4-hydroxy-3-methoxybenzaldehyde 
• 621-59-0 isovanillin 

Downstream Products

• 891148-72-4 C₁₉H₁₇BrO₇S 
• 6948-30-7 5-bromoveratralaldehyde 
• 1286210-10-3 C₂₅H₂₈O₃Si 
• 1286210-26-1 C₃₉H₄₂ClNO₆Si 
• 1286210-50-1 C₃₉H₄₀ClNO₆Si 
• 1286210-34-1 C₃₉H₄₂ClNO₆Si 
• 1286210-52-3 C₄₁H₄₄ClNO₇Si 
• 1286210-43-2 C₂₃H₂₅BrO₃Si 
• 1286210-20-5 C₂₄H₂₅BrO₃Si 
• 16414-34-9 3-bromo-4,5-dihydroxybenzaldehyde 
• 645-08-9 Isovanillic acid 
• 511257-19-5 2-benzyloxyimino-3-(4-{5-[2-benzyloxyimino-2-(2-{3-bromo-4-[3-bromo-5-(2-tert-butoxycarbonylamino-ethyl)-2-methoxy-phenoxy]-phenyl}-ethylcarbamoyl)-ethyl]-3-bromo-2-methoxy-phenoxy}-5-bromo-2-nitro-phenyl)-propionic acid pentafluorophenyl ester 
• 511257-18-4 2-[(E)-Benzyloxyimino]-3-(4-{5-[2-[(E)-benzyloxyimino]-2-(2-{3-bromo-4-[3-bromo-5-(2-tert-butoxycarbonylamino-ethyl)-2-methoxy-phenoxy]-phenyl}-ethylcarbamoyl)-ethyl]-3-bromo-2-methoxy-phenoxy}-5-bromo-2-nitro-phenyl)-propionic acid ethyl ester 

Relevant articles and documents

PYRIMIDONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyrimidone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment or prophylaxis of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

Synthesis and antitumor activity of feruloyl and caffeoyl derivatives This paper is dedicated to Prof. Wei-xiao Hu for his lifelong commitment to mentoring graduate students

We developed two efficient protocols for the synthesis of feruloyl and caffeoyl derivatives from commercial vanillin and veratraldehyde. Pharmacological activities were assessed against a panel of human cancer cell lines in vitro. Most synthesized compounds demonstrated attractive cytotoxicity. Several new compounds demonstrated significant antiproliferative and cytotoxic activities against HeLa and Bewo tumor cell lines. In particular, 5-nitro caffeic adamantyl ester showed broad spectrum of tumor inhibition in 10 cell lines, and reduced tumor weight by 36.7% in vivo when administered at a dose of 40 mg kg-1.

Synthesis and biological evaluation of ABCD ring fragments of the kibdelones

Arylation goes platinum: The synthesis of the ABCD ring fragments of the kibdelones has been achieved through a novel PtIV-catalyzed arylation of a quinone monoketal followed by photocyclization (see scheme). Biological evaluation in the NCI 60-cell screen revealed that the kibdelone ABCD ring analogues were about 2000 times less active than kibdelones B and C, suggesting that the tetrahydroxanthone structure of the kibdelones is crucial for cytotoxicity. Copyright