23361-28-6

Basic information

• Product Name: BOC-VAL-PRO-OH
• Synonyms: BOC-L-VALYL PROLINE;BOC-VAL-PRO-OH;N-BOC-L-VALYL-L-PROLINE;N-tert-Butoxycarbonyl-L-valyl-L-proline;Boc-Val-Pro;L-Proline, N-[(1,1-diMethylethoxy)carbonyl]-L-valyl-;Boc-L-Val-L-Pro-OH;-3-methylbutanoyl)
• CAS NO: 23361-28-6
• Molecular Formula: C₁₅H₂₆N₂O₅
• Molecular Weight: 314.38
• Mol File: 23361-28-6.mol
• Article Data: 19

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 503.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.171±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.50±0.20(Predicted)
• CAS DataBase Reference: BOC-VAL-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-VAL-PRO-OH(23361-28-6)
• EPA Substance Registry System: BOC-VAL-PRO-OH(23361-28-6)

Safety Data

• Hazardous Substances Data: 23361-28-6(Hazardous Substances Data)

Usage

General Description

BOC-VAL-PRO-OH is a chemical compound that is composed of three amino acids: valine, proline, and hydroxyproline, with a Boc (tert-butoxycarbonyl) protecting group attached to the amino group of valine. BOC-VAL-PRO-OH is commonly used as a building block in peptide synthesis, where the Boc protecting group can be selectively removed to reveal the reactive amine group of valine. BOC-VAL-PRO-OH has applications in the production of pharmaceuticals, agrochemicals, and materials science, as well as in research and development. Its unique structure and reactivity make it a valuable tool for creating complex peptide sequences and scaffolds for a wide range of applications.

Upstream product

• 38017-75-3 N-tert-butoxycarbonyl-L-valyl-L-proline methyl ester 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 13734-41-3 t-Boc-L-valine 
• 147-85-3 L-proline 
• 5817-26-5 ethyl (2S)-pyrrolidine-2-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 72-18-4 L-valine 
• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 
• 58872-03-0 1--L-valyl>-L-proline phenylmethyl ester 
• 66866-46-4 C₁₅H₂₇NO₆ 
• 7364-47-8 (S)-trimethylsilyl 1-(trimethylsilyl)pyrrolidine-2-carboxylate 
• 3392-12-9 Boc-Val-ONSu 

Downstream Products

• 191597-53-2 (3R,4S)-4-{[(S)-1-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-2,2-difluoro-3-hydroxy-5-phenyl-pentanoic acid ethyl ester 
• 191597-68-9 (3S,4R)-4-{[(S)-1-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyryl)-pyrrolidine-2-carbonyl]-amino}-2,2-difluoro-3-hydroxy-5-phenyl-pentanoic acid ethyl ester 
• 211426-90-3 Boc-Val-Pro-Phe-Trp-OMe 
• 847256-25-1 [(S)-1-((S)-2-Benzylcarbamoyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-carbamic acid tert-butyl ester 
• 74084-07-4 Boc-Val-Pro-Ile-Phe-Thr-Tyr-Gly-OEt 
• 112383-16-1 N-t-butoxycarbonyl-L-valyl-L-prolyl-α-azanorvaline benzyl ester 
• 124511-34-8 Boc-Val-Leu-D-Phe-Pro-OBzl 
• 109953-34-6 Boc-Val-Pro-Azala-OBzl 

Relevant articles and documents

Inhibition of urease enzyme activity by urea and thiourea derivatives of dipeptides conjugated 2, 3-dichlorophenyl piperazine

Objective: Studies on enzyme inhibition remain an important area of pharmaceutical research since these studies have led to the discoveries of drugs used in a variety of physiological conditions. In search of novel urease enzyme inhibitors, four dipeptide

Stereochemical basis for the anti-chlamydial activity of the phosphonate protease inhibitor JO146

JO146, a mixture of two diastereomers of a peptidic phosphonate inhibitor for Chlamydial HtrA (CtHtrA), has reported activity against Chlamydia species in both human and koala. In this study we isolated the individual diastereomers JO146-D1 and JO146-D2 (

NOVEL DIPEPTIDYL PEPTIDASE (DP-IV) COMPOUNDS

The present invention is directed to novel compounds of formula I and pharmaceutically acceptable salts, enantiomers thereof having inhibiting properties of dipeptidyl peptidase IV enzyme (DP-IV inhibitors). The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds along with its composition in the prevention or treatment of diseases associated with DP-IV enzyme. wherein, A is defined as R3-R4 wherein R3 and R4 are together or independently defined as peptides having amino acids ranging from 1 to 10, B is chemical bond between peptide and substituted amine, R1, and R2 are as defined in specification,