23384-33-0

Basic information

• Product Name: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methoxyphenyl)-
• CAS NO: 23384-33-0
• Molecular Formula: C8H8F3NO3S
• Molecular Weight: 255.218
• Mol File: 23384-33-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methoxyphenyl)-(23384-33-0)
• EPA Substance Registry System: Methanesulfonamide, 1,1,1-trifluoro-N-(3-methoxyphenyl)-(23384-33-0)

Safety Data

• Hazardous Substances Data: 23384-33-0(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 536-90-3 m-Anisidine 
• 3855-45-6 triflic azide 
• 100-66-3 methoxybenzene 

Downstream Products

• 1421622-86-7 N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-hydroxypropyl)-1,1,1-trifluoro-N-(3-methoxyphenyl)methanesulfonamide 
• 1421622-48-1 N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-1,1,1-trifluoro-N-(3-methoxyphenyl)methanesulfonamide 
• 1235481-90-9 N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline 
• 1421622-47-0 (E)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)prop-1-en-1-yl)-1,1,1-trifluoro-N-(3-methoxyphenyl)methanesulfonamide 
• 1447967-39-6 3,6-dibromo-9-((1-(3-methoxyphenyl)aziridin-2-yl)methyl)-9H-carbazole 
• 66476-52-6 N-(Trifluormethyl-sulfonyl)-4,6-bis-(trifluormethylthio)-3-methoxy-anilin 

Relevant articles and documents

Diamination of Domino Aryne Precursor with Sulfonamides

The reaction of a domino aryne precursor with sulfonamides efficiently afforded both 1,3-diaminobenzenes and trisubstituted 1,3-diaminobenzenes by simply varying the reaction conditions. Mechanistic study supports the sequential formation of two transient aryne intermediates involved in the reaction.

Development of a scalable synthesis of P7C3-A20, a potent neuroprotective agent

A scalable synthesis of the neuroprotective agent P7C3-A20 is described. The synthesis has provided hundred-gram batches of the final compound for biological evaluation in rodents primates. The synthesis can be performed without chromatographic purificati