23443-05-2 Usage
General Description
5-Chloroquinolin-4-ol is a chemical compound with the molecular formula C9H6ClNO. It is a chlorinated derivative of quinolin-4-ol, also known as 4-hydroxyquinoline. 5-chloroquinolin-4-ol is a heterocyclic aromatic organic compound with a chlorine atom attached to the fifth carbon in the quinoline ring. 5-Chloroquinolin-4-ol is commonly used in the synthesis of pharmaceuticals and agrochemicals, and it also has antimicrobial and antifungal properties. Its unique chemical structure and properties make it a valuable building block for the production of various chemical compounds for pharmaceutical and agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 23443-05-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,4,4 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23443-05:
(7*2)+(6*3)+(5*4)+(4*4)+(3*3)+(2*0)+(1*5)=82
82 % 10 = 2
So 23443-05-2 is a valid CAS Registry Number.
23443-05-2Relevant articles and documents
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities
Madrid, Peter B.,Sherrill, John,Liou, Ally P.,Weisman, Jennifer L.,DeRisi, Joseph L.,Guy, R. Kiplin
, p. 1015 - 1018 (2007/10/03)
A simple two-step synthesis method was used to make 51 B-ring-substituted 4-hydroxyquinolines allowing analysis of the effect of ring substitutions on inhibition of growth of chloroquine sensitive and resistant strains of Plasmodium falciparum, the dominant cause of malaria morbidity. Substituted quinoline rings other than the 7-chloroquinoline ring found in chloroquine were found to have significant activity against the drug-resistant strain of P. falciparum W2.