235092-07-6

Basic information

• Product Name: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylthio)oxy]-, ethyl ester, (3-endo)-
• CAS NO: 235092-07-6
• Molecular Formula: C16H21NO3S
• Molecular Weight: 307.414
• Mol File: 235092-07-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylthio)oxy]-, ethyl ester, (3-endo)-(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylthio)oxy]-, ethyl ester, (3-endo)-(235092-07-6)
• EPA Substance Registry System: 8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-[(phenylthio)oxy]-, ethyl ester, (3-endo)-(235092-07-6)

Safety Data

• Hazardous Substances Data: 235092-07-6(Hazardous Substances Data)

Upstream product

• 30833-12-6 ethyl 3-endo-3-hydroxy-8-azabicyclo[3.3.1]octane-8-carboxylate 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 32499-64-2 N-carbethoxytropinone 
• 30833-12-6 ethyl 3-endo-3-hydroxy-8-azabicyclo[3.3.1]octane-8-carboxylate 

Relevant articles and documents

Synthesis of acetyl scopine. Intramolecular reactions of N-carbethoxy nortropine-3α-benzene-sulfenate

The synthesis of acetyl scopine using tropine as a starting compound was achieved. Free radical phenylthio group transfer to the 6-position, in the reaction of N-carbethoxy nortropine-3α-benzenesulfenate with hexabutylditin, is a key step of this synthetic approach to scopine. The reaction of N- carbethoxy nortropine-benzenesulfenate with tributyltin hydride in the presence of a radicophilic olefin involves Michael type alkylation at the 6- position of tropine skeleton affording 6-(2-carbethoxyethyl)-N-carbethoxy nortropine in 31% yield.