23510-18-1

Basic information

• Product Name: benzyl-(2-chloroethyl)-methyl-azanium chloride
• Synonyms: benzyl-(2-chloroethyl)-methyl-azanium chloride;N-(2-chloroethyl)-N-MethylbenzylaMine Hydrochloride;BenzeneMethanaMine,N-(2-chloroethyl)-N-Methyl-, hydrochloride;N-(2-Chloroethyl)-N-methylbenzylamine hydrochloride, N-Benzyl-N-(2-chloroethyl)methylamine hydrochloride;N-Benzyl-2-chloro-N-methylethylamine hydrochloride;N-Benzyl-2-chloro-N-methylethanamine hydrochloride;N-(2-CHLOROETHYL)-N-METHYLBENZYLAMINE HCL
• CAS NO: 23510-18-1
• Molecular Formula: C₁₀H₁₄ClN*ClH
• Molecular Weight: 0
• Mol File: 23510-18-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 140-141℃
• Boiling Point: 205.3°Cat760mmHg
• Flash Point: 77.9°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 0.252mmHg at 25°C
• CAS DataBase Reference: benzyl-(2-chloroethyl)-methyl-azanium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl-(2-chloroethyl)-methyl-azanium chloride(23510-18-1)
• EPA Substance Registry System: benzyl-(2-chloroethyl)-methyl-azanium chloride(23510-18-1)

Safety Data

• Hazardous Substances Data: 23510-18-1(Hazardous Substances Data)

Usage

General Description

Benzyl-(2-chloroethyl)-methyl-azanium chloride is a chemical compound with the molecular formula C9H12ClN. It is a quaternary ammonium salt that contains a benzyl group, a 2-chloroethyl group, and a methyl group attached to a central nitrogen atom. The chloride ion is associated with the cationic part of the molecule. benzyl-(2-chloroethyl)-methyl-azanium chloride has applications in organic synthesis, particularly in the production of quaternary ammonium salts and other related organic compounds. It is also used as a reagent in chemical reactions and as an intermediate in pharmaceutical synthesis. In addition, it has potential applications in the field of medicine and may be used in the development of new drugs or as a precursor for pharmaceutical compounds.

InChI:InChI=1/C10H14ClN.ClH/c1-12(8-7-11)9-10-5-3-2-4-6-10;/h2-6H,7-9H2,1H3;1H

Upstream product

• 103-67-3 benzyl-methyl-amine 
• 101-98-4 2-(N-benzyl-N-methyl)amino-1-ethanol 

Downstream Products

• 102462-14-6 1-[2-(benzyl-methyl-amino)-ethyl]-4-phenyl-piperazine 
• 102-11-4 N-benzyl-N-methyl-N'-methylethylenediamine 
• 159898-41-6 5-(Benzyl-methyl-amino)-3-(3,4-dimethoxy-phenyl)-pentan-2-one 
• 502769-45-1 2-benzyl-2-[2-(N-benzyl-N-methylamino)ethyl]malonic acid diethyl ester 
• 884850-53-7 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N-benzyl-N-methylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 
• 150046-78-9 2-[2-(N-Benzyl-N-methylamino)ethyl]-1,3-dihydroisoindole 
• 150046-75-6 2-(N-Benzyl-N-methylamino)-1-(N-piperidinyl)ethane 
• 1253203-57-4 9-(2-(benzyl(methyl)amino)ethoxy)-7H-furo[3,2-g]chromen-7-one 
• 1254704-99-8 N₁-benzyl-N₁-methyl-N₂-phenyl-N₂-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)ethane-1,2-diamine 
• 1226802-14-7 4-[1-[2-(benzyl-methyl-amino)-ethyl]-4-(3-chloro-4-fluoro-phenyl)-1H-imidazol-2-yl]-piperidine-1-carboxylic acid tert-butyl ester 
• 73540-31-5 7-[2-(N-benzyl-N-methylamino)ethoxy]-2,2-dimethyl-4-(2-naphthyl)-2H-chromene 
• 73540-30-4 2,2-dimethyl-4-(2-naphthyl)-7-[2-(1-piperidino)ethoxy]-2H-chromene 
• 100893-21-8 (-)-cis-2-(4-methoxyphenyl)-3-acetoxy-5-[2-(N-benzyl-N-methylamino)ethyl]-8-chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 
• 100893-18-3 (-)-cis-2-(4-methoxyphenyl)-3-hydroxy-5-[2-(N-benzyl-N-methylamino)ethyl]-8-chloro-2,3-dihydro-1,5-benzothiazepin-4(5H)-one 

Relevant articles and documents

Design, Synthesis and Preliminary Evaluation of Novel Imperatorin Derivatives as Vasorelaxant Agents

A series of novel imperatorin derivatives were synthesized from commercially available xanthotoxin. The in vitro pharmacological evaluation indicated that all of the compounds possessed potent vasodilatory activity. Among them, compounds (5b), (5d) and (5e) exhibited higher vasdilatory activity (with EC50 values of 0.68 μM, 0.59 μM and 0.49 μM, respectively) than imperatorin (EC50 = 1.12 μM). The program Volsurf was used to predict the derivatives' ADMErelevant descriptors. The results suggested that these novel compounds had a potential interest for the development of novel and potent vasorelaxant agents.

Diaryldiamines with dual inhibition of the histamine H3 receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1- phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain

A series of compounds was designed as dual inhibitors of the H3 receptor and the norepinephrine transporter. Compound 5 (rNET Ki = 14 nM; rH3R Ki = 37 nM) was found to be efficacious in a rat model of osteoarthritic pain.

6-Substituted 6H-dibenzo[c,h][2,6]naphthyridin-5-ones: Reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxicity

6-Substituted 8,9-dimethoxy-2,3-methylenedioxy-6H-dibenzo[c,h][2,6] naphthyridin-5-ones were synthesized and evaluated for topoisomerase I-targeting activity and cytotoxicity. Several of these reversed lactam analogues of ARC-111 exhibited exceptional cyt