23596-02-3

Basic information

• Product Name: 4-ACETYL-N-(4-METHOXYBENZYLIDENE)ANILIN&
• Synonyms: 4-ACETYL-N-(4-METHOXYBENZYLIDENE)ANILIN&;1-(4-(((4-Methoxyphenyl)methylene)amino)phenyl)ethanone, 4μ-((4-Methoxybenzylidene)amino)acetophenone
• CAS NO: 23596-02-3
• Molecular Formula: C₁₆H₁₅NO₂
• Molecular Weight: 253.2958
• Mol File: 23596-02-3.mol
• Article Data: 8

Chemical Properties

• Melting Point: 122-124 °C(lit.)
• Boiling Point: 425.8oC at 760 mmHg
• Flash Point: 193.1oC
• Appearance: /
• Density: 1.05g/cm3
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.547
• PKA: 2.73±0.50(Predicted)
• CAS DataBase Reference: 4-ACETYL-N-(4-METHOXYBENZYLIDENE)ANILIN&(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETYL-N-(4-METHOXYBENZYLIDENE)ANILIN&(23596-02-3)
• EPA Substance Registry System: 4-ACETYL-N-(4-METHOXYBENZYLIDENE)ANILIN&(23596-02-3)

Safety Data

• Hazard Codes: Xi,N
• Statements: 51/53
• Safety Statements: 36/37-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 23596-02-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H15NO2/c1-12(18)14-5-7-15(8-6-14)17-11-13-3-9-16(19-2)10-4-13/h3-11H,1-2H3/b17-11+

Upstream product

• 100-19-6 (4-nitrophenyl)ethanone 
• 105-13-5 4-Methoxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 
• 99-92-3 p-aminobenzophenone 

Downstream Products

• 405103-36-8 1-(4-((4-methoxybenzyl)amino)phenyl)ethan-1-one 
• 1370225-47-0 (4-{1-[(7-chloro-quinolin-4-yl)-hydrazono]-ethyl}-phenyl)-(4-methoxy-benzylidene)-amine 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 7443-25-6 dimethyl 2-(4-methoxybenzylidene)malonate 
• 2286-29-5 ethyl 2-cyano-3-(4-methoxyphenyl)prop-2-enoate 
• 38131-68-9 4-(4-dimethylaminobenzylidene)aminoacetophenone 
• 115848-62-9 3-(4-acetophenyl)-2-(p-methoxyphenyl)thiazolidin-4-one 

Relevant articles and documents

Synthesis, characterization and theoretical study in gaseous and solid phases of the imine 4-Acetyl-N-(4-methoxybenzylidene)aniline

In the present paper we describe the synthesis and characterization of the Schiff's base or imine 4-Acetyl-N-(4-methoxybenzylidene)aniline (1), which provided experimental support for the theoretical calculations. The imine was characterized by infrared s

Visible-Light Photocatalytic Synthesis of Amines from Imines via Transfer Hydrogenation Using Quantum Dots as Catalysts

CdSe/CdS core/shell quantum dots (QDs) can be used as stable and highly active photoredox catalysts for efficient transfer hydrogenation of imines to amines with thiophenol as a hydrogen atom donor. This reaction proceeds via a proton-coupled electron transfer (PCET) from the QDs conduction band to the protonated imine followed by hydrogen atom transfer from the thiophenol to the α-aminoalkyl radical. This precious metal free transformation is easy to scale up and can be carried out by a one-pot protocol directly from aldehyde, amine, and thiophenol. Additional advantageous features of this protocol include a wide substrate scope, high yield of the amine products, extremely low catalyst loading (0.001 mol %), high turnover number (105), and the mild reaction conditions of using visible light or sun light at room temperature in neutral media.

Design, synthesis and in vitro antimalarial evaluation of new quinolinylhydrazone derivatives

A series of novel quinolinylhydrazones (5a-f) was synthesized by the condensation reaction of 2,6-diaryl-substituted piperidin-4-ones (4a-f) with 7-chloro-4-hydrazinoquinoline (2). Novel quinolinylhydrazones containing Shiff bases 8a-f and 11a-f were obta