236414-37-2Relevant articles and documents
Development of Peptide-Based Sirtuin Defatty-Acylase Inhibitors Identified by the Fluorescence Probe, SFP3, That Can Efficiently Measure Defatty-Acylase Activity of Sirtuin
Kawaguchi, Mitsuyasu,Ieda, Naoya,Nakagawa, Hidehiko
, p. 5434 - 5452 (2019/06/17)
Sirtuins (SIRTs) are a family of nicotinamide adenine dinucleotide-dependent histone deacetylases that serve as epigenetic regulators of many physiological processes. Recent studies have shown that in addition to their well-known deacetylase activity, sir
Inhibitors of the NAD+-dependent protein desuccinylase and demalonylase sirt5
Maurer, Benjamin,Rumpf, Tobias,Scharfe, Michael,Stolfa, Diana A.,Schmitt, Martin L.,He, Wenjuan,Verdin, Eric,Sippl, Wolfgang,Jung, Manfred
supporting information, p. 1050 - 1053 (2013/02/23)
NAD+-dependent histone deacetylases (sirtuins) play important roles in epigenetic regulation but also through nonhistone substrates for other key cellular events and have been linked to the pathogenesis of cancer, neurodegeneration, and metabol