23652-56-4Relevant articles and documents
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Grob
, p. 1787,1795 (1950)
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Rh(I)-catalyzed enantioselective hydrogenation of (E)- and (Z)-beta-(acylamino)acrylates using 1,4-bisphosphine ligands under mild conditions.
Lee, Sang-gi,Zhang, Yong Jian
, p. 2429 - 2431 (2002)
[reaction: see text] Rh-Me-BDPMI (1a) complex can be an effective catalyst for the hydrogenations of (E)- and (Z)-beta-(acylamino)acrylates, in which the Z-isomers hydrogenated with the same or even higher ee values than the corresponding E-isomers. The conversion yield and enantioselectivity of E- and Z-isomers were largely dependent on the solvent, and thus, the E-isomers were hydrogenated more effectively in CH(2)Cl(2), whereas the Z-isomers were hydrogenated more effectively in polar MeOH solvent.
Hypervalent iodane mediated reactions of: N -acetyl enamines for the synthesis of oxazoles and imidazoles
Xu, Kang,Yang, Ruiqi,Yang, Shuang,Jiang, Cheng,Ding, Zhenhua
supporting information, p. 8977 - 8981 (2019/10/28)
A hypervalent iodane reagent used for the intramolecular cyclization of N-acetyl enamines and intermolecular cyclocondensation of enamines and nitriles was investigated. The reaction was performed under mild conditions and gave oxazoles and imidazoles, respectively, in moderate to excellent yields. This transformation exhibits good reactivity, selectivity and functional group tolerance. The selectivity of the intra- or intermolecular reaction is dependent on the structure of N-acetyl enamines.
A optically active 3 - amino butanol and 3 - aminobutyric acid preparation method (by machine translation)
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Paragraph 0107; 0108, (2017/07/01)
The invention discloses a method of optically active 3 - amino butanol and 3 - aminobutyric acid preparation method. Wherein optically active 3 - amino butyl alcohol preparation method comprises the following steps: in a solvent, in the borohydride reducing agent and a Lewis acid under the action of the, shown as 65 shown in the reduction reaction of compound, production like type 14 indicated by the compound. Optically active 3 - aminobutyric acid preparation method comprises the following steps: shown as 64 a compound represented by the hydrolytic reaction, production like type 65 compound of formula. Preparation method of this invention the raw material is cheap, simple operation, the process route is short, the raw material is not hazardous, high yield, produce little material waste, is beneficial for the protection of the environment, high conversion rate of raw materials, product chemical purity and high optical purity, and is easy to realize industrial. (by machine translation)