2367-91-1

Basic information

• Product Name: 1-Chloro-2,5-difluorobenzene
• Synonyms: Benzene,2-chloro-1,4-difluoro-;2-CHLORO-1,4-DIFLUOROBENZENE;2,5-DIFLUOROCHLOROBENZENE;1-CHLORO-2,5-DIFLUOROBENZENE;1-CHLORO-2 5-DIFLUOROBENZENE 98%;1-Chloro-2,5-difluorobenzene, 98% [2-Chloro-1,4-difluorobenzene];1-Chloro-2,5-difluorobenzene98%;1-Chloro-2,5-difluor
• CAS NO: 2367-91-1
• Molecular Formula: C₆H₃ClF₂
• Molecular Weight: 148.54
• EINECS: -0
• Product Categories: Aryl;C6;Halogenated Hydrocarbons
• Mol File: 2367-91-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 24.6 °C
• Boiling Point: 126-128 °C(lit.)
• Flash Point: 68 °F
• Appearance: liquid
• Density: 1.352 g/mL at 25 °C(lit.)
• Refractive Index: n20/D 1.478(lit.)
• Storage Temp.: 2-8°C
• BRN: 2081082
• CAS DataBase Reference: 1-Chloro-2,5-difluorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Chloro-2,5-difluorobenzene(2367-91-1)
• EPA Substance Registry System: 1-Chloro-2,5-difluorobenzene(2367-91-1)

Safety Data

• Hazard Codes: Xn,F,Xi
• Statements: 10-20/21/22-36/37-36/37/38-11
• Safety Statements: 16-26-36-37/39
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 2367-91-1(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C6H3ClF2/c7-5-3-4(8)1-2-6(5)9/h1-3H

Upstream product

• 540-36-3 para-difluorobenzene 
• 108-90-7 chlorobenzene 
• 367-21-5 3-chloro-4-fluorophenylamine 
• 60-29-7 diethyl ether 

Downstream Products

• 224168-12-1 ethyl (4-chloro-3,6-difluoro-2-nitrophenyl)carbamate 
• 408492-25-1 2-(2,5-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 261762-39-4 2-chloro-3,6-difluorobenzaldehyde 
• 886501-33-3 2-chloro-3,6-difluoro-benzonitrile 

Relevant articles and documents

Reactions of aromatic compounds with xenon difluoride

Reactions of substituted benzenes C6H5R (R = Me, F, Cl, Br, CF3, NO2) with xenon difluoride in the presence of boron trifluoride–diethyl ether complex in weakly acidic (1,1,1,3,3-pentafluorobutane) and weakly basic media (acetonitrile) have been studied. These reactions lead to the formation of fluorobenzene derivatives FC6H4R (isomer mixture) together with isomeric difluorobenzenes and fluorinated and non-fluorinated biphenyls. The results have been compared with previously reported data obtained in other solvents using other catalysts.

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.