23676-58-6Relevant articles and documents
Structure-dependent tautomerization induced catalyst-free autocatalyzed N-alkylation of heteroaryl amines with alcohols
Li, Shuangyan,Li, Xiaohui,Li, Qiang,Yuan, Qiaochao,Shi, Xinkang,Xu, Qing
supporting information, p. 3260 - 3265 (2015/06/25)
Catalyst-free autocatalyzed dehydrative N-alkylation reactions of 2-aminobenzothiazoles, 2-aminopyrimidines, and 2-aminopyrazine with primary and secondary alcohols have been achieved for efficient, practical, and green synthesis of the versatile heteroaryl amine derivatives. These reactions were interestingly induced by structure-dependent tautomeric equilibria of the heteroaryl amines via MPV-O transfer hydrogenation of the imino tautomers by alcohols to give aldehydes as the key initiating step.
Manganese dioxide catalyzed N-alkylation of sulfonamides and amines with alcohols under air
Yu, Xiaochun,Liu, Chuanzhi,Jiang, Lan,Xu, Qing
supporting information; experimental part, p. 6184 - 6187 (2012/01/06)
By simply running the reactions under air and solvent-free conditions using catalytic amounts of manganese dioxide, a practical and efficient N-alkylation method for a variety of sulfonamides and amines using alcohols as green alkylating reagents was developed.
