237431-64-0

Basic information

• Product Name: 2H-1,3-Benzoxazine, 3,4-dihydro-6-methyl-3-[(1R)-1-phenylethyl]-
• CAS NO: 237431-64-0
• Molecular Formula: C17H19NO
• Molecular Weight: 253.344
• Mol File: 237431-64-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2H-1,3-Benzoxazine, 3,4-dihydro-6-methyl-3-[(1R)-1-phenylethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1,3-Benzoxazine, 3,4-dihydro-6-methyl-3-[(1R)-1-phenylethyl]-(237431-64-0)
• EPA Substance Registry System: 2H-1,3-Benzoxazine, 3,4-dihydro-6-methyl-3-[(1R)-1-phenylethyl]-(237431-64-0)

Safety Data

• Hazardous Substances Data: 237431-64-0(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 106-44-5 p-cresol 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 82807-53-2 4-methyl-2-(4-morpholinylmethyl)phenol 
• 569646-46-4 4-Methyl-2-{[morpholin-4-ylmethyl-((R)-1-phenyl-ethyl)-amino]-methyl}-phenol 
• 3534-33-6 3,4-dihydro-3,6-dimethyl-2H-1,3-benz[e]oxazine 
• 237431-66-2 2-hydroxy-5-methyl-N-methylbenzylamine 
• 7204-35-5 2-(dimethylamino-methyl)-4-methyl-phenol 
• 569646-47-5 4-Methyl-2-[((R)-1-phenyl-ethylamino)-methyl]-phenol 
• 237431-65-1 4-Methyl-2-{[methyl-((R)-1-phenyl-ethyl)-amino]-methyl}-phenol 

Relevant articles and documents

Retro-Mannich reactions of 3-alkyl-3,4-dihydro-2H-1,3-benz[e]oxazines and the synthesis of axially chiral resorcinarenes

Intermediates involved in the conversion of 3-alkyl-3,4-dihydro-2H-1,3-benz[e]oxazines into 2-N,N-dialkylaminomethylphenol derivatives, using morpholine and other high boiling secondary amines, have been identified and characterised. Additional experiments have established the involvement of o-quinone methide intermediates in the retro-Mannich reactions. Axially chiral resorcinarenes have been prepared by utilising the exchange reactions.