23767-27-3Relevant articles and documents
Synthesis and In Vitro Anticancer Activity of Novel 1,3,4-Oxadiazole-Linked 1,2,3-Triazole/Isoxazole Hybrids
Madhavilatha,Bhattacharjee, Debanjan,Sabitha, Gowravaram,Reddy, B. V. Subba,Yadav,Jain, Nishant,Reddy, B. Jagan Mohan
, p. 863 - 870 (2018/02/12)
A series of new 1,3,4-oxadiazole-linked 1,2,3-triazole/isoxazole derivatives were designed and synthesized. All the synthesized compounds were screened for in vitro anticancer activity against four human cancer cells: HeLa (cervical), MDA-MB-231 (breast), DU-145 (prostate), and HEPG2 (liver). Among 17 compounds tested, 7a, 7c, and 7d showed potent activity toward four cell lines.