23786-14-3

Basic information

• Product Name: METHYL 4-METHOXYPHENYLACETATE
• Synonyms: Acetic acid, (p-methoxyphenyl)-, methyl ester;Acetic acid, 4-methoxyphenoxy, methyl ester;Methyl 2-(p-methoxyphenyl)acetate;Phenylacetic acid, 4-methoxy, methyl ester;4-METHOXYPHENYLACETIC ACID METHYL ESTER;ASISCHEM D13374;AURORA KA-6001;METHYL 4-METHOXYPHENYLACETATE
• CAS NO: 23786-14-3
• Molecular Formula: C₁₀H₁₂O₃
• Molecular Weight: 180.2
• EINECS: 245-886-1
• Product Categories: Aromatic Esters;C10 to C11;Carbonyl Compounds;Esters
• Mol File: 23786-14-3.mol
• Article Data: 115

Chemical Properties

• Boiling Point: 158 °C19 mm Hg(lit.)
• Flash Point: 98 °F
• Appearance: yellow-green/liquid
• Density: 1.135 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.000151mmHg at 25°C
• Refractive Index: n20/D 1.516(lit.)
• Storage Temp.: Flammables area
• BRN: 2209665
• CAS DataBase Reference: METHYL 4-METHOXYPHENYLACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-METHOXYPHENYLACETATE(23786-14-3)
• EPA Substance Registry System: METHYL 4-METHOXYPHENYLACETATE(23786-14-3)

Safety Data

• Statements: 10
• Safety Statements: 16-24/25
• RIDADR: UN 3272 3/PG 3
• WGK Germany: 3
• F: 10
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 23786-14-3(Hazardous Substances Data)

Usage

Description

METHYL 4-METHOXYPHENYLACETATE is an organic compound with the chemical formula C10H12O3. It is a clear colorless to yellow liquid and is commonly used in the synthesis of various compounds, including 7,8-dihydroxy-2-(4′-hydroxybenzyl)-4H-1-benzopyran-4-one.

Uses

Used in Pharmaceutical Industry:
METHYL 4-METHOXYPHENYLACETATE is used as an intermediate compound for the synthesis of various pharmaceuticals. Its role in the synthesis of 7,8-dihydroxy-2-(4′-hydroxybenzyl)-4H-1-benzopyran-4-one highlights its importance in the development of new drugs and therapeutic agents.
Used in Chemical Synthesis:
METHYL 4-METHOXYPHENYLACETATE is used as a reagent in the chemical synthesis of various organic compounds. Its versatility as a starting material allows for the creation of a wide range of products, making it a valuable asset in the field of organic chemistry.
Used in Research and Development:
METHYL 4-METHOXYPHENYLACETATE is utilized in research and development for the exploration of new chemical reactions and the discovery of novel compounds with potential applications in various industries, including pharmaceuticals, materials science, and agriculture.

InChI:InChI=1/C10H12O4/c1-13-8-5-3-7(4-6-8)9(11)10(12)14-2/h3-6,9,11H,1-2H3

Upstream product

• 84508-63-4 2-chloro-1,1-dimethoxy-1-(4-methoxyphenyl)ethane 
• 80336-71-6 2-iodo-1,1-dimethoxy-1-(4-methoxyphenyl)ethane 
• 67-56-1 methanol 
• 104-01-8 4-Methoxyphenylacetic acid 
• 156-38-7 4-hydroxyphenylacetate 
• 74-88-4 methyl iodide 
• 6832-17-3 2-diazo-1-(4-methoxyphenyl)ethanone 
• 532-31-0 silver benzoate 
• 6343-93-7 2-(4-methoxyphenyl)acetamide 
• 201230-82-2 carbon monoxide 
• 616-38-6 carbonic acid dimethyl ester 
• 105-13-5 4-Methoxybenzyl alcohol 
• 60512-57-4 1-(2,2-dibromovinyl)-4-methoxybenzene 
• 54159-16-9 (2-<2H1>)-4-methoxyphenylethyne 

Downstream Products

• 104-01-8 4-Methoxyphenylacetic acid 
• 6343-93-7 2-(4-methoxyphenyl)acetamide 
• 38558-72-4 2,5-dihydroxy-3,6-bis-(4-methoxy-phenyl)-[1,4]benzoquinone 
• 56369-49-4 (4-methoxy-phenyl)-acetic acid-(2-hydroxy-ethylamide) 
• 14062-18-1 ethyl p-methoxyphenylacetate 
• 1025800-84-3 1-(2-hydroxy-5-methoxy-phenyl)-4-(4-methoxy-phenyl)-butane-1,3-dione 
• 18503-98-5 2-Methyl-2-chlor-3-<4-methoxy-phenyl>-propan 
• 33155-61-2 tert-butyl 2-(4-methoxyphenyl)acetate 
• 74587-15-8 benzyl 2-(4-methoxyphenyl)ethanoate 
• 75600-94-1 methyl (4-methoxyphenyl)glyoxylate phenylhydrazone 
• 127933-99-7 2-(4-methyloxyphenyl)pentanedioic acid dimethyl ester 
• 15727-84-1 4'-Methoxyphenylessigsaeureallylester 
• 137346-00-0 methyl (3-azido-4-methoxyphenyl)acetate 
• 588-14-7 (3-fluoro-4-methoxyphenyl)acetic acid methyl ester 

Relevant articles and documents

SUBSTITUTED PIPERAZINE DERIVATIVES USEFUL AS T CELL ACTIVATORS

Disclosed are compounds of Formula (I): or a salt thereof, wherein: R1, R2, R4, R5, R6, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGKα) and diacylglycerol kinase zeta (DGKζ), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.

B(C6F5)3-catalyzed O-H insertion reactions of diazoalkanes with phosphinic acids

A highly efficient base-, metal-, and oxidant-free catalytic O-H insertion reaction of diazoalkanes and phosphinic acids in the presence of B(C6F5)3has been developed. This powerful methodology provides a green approach towards the synthesis of a broad spectrum of α-phosphoryloxy carbonyl compounds with good to excellent yields (up to 99% yield). The protocol features the advantages of operational simplicity, high atom economy, practicality, easy scalability and environmental friendliness.

Electrochemical oxidative: Z -selective C(sp2)-H chlorination of acrylamides

An electrochemical method for the oxidative Z-selective C(sp2)-H chlorination of acrylamides has been developed. This catalyst and organic oxidant free method is applicable across various substituted tertiary acrylamides, and provides access to a broad range of synthetically useful Z-β-chloroacrylamides in good yields (22 examples, 73% average yield). The orthogonal derivatization of the products was demonstrated through chemoselective transformations and the electrochemical process was performed on gram scale in flow.