23794-73-2

Basic information

• Product Name: CarbaMic acid, N-[4-(trifluoroMethyl)phenyl]-, ethyl ester
• Synonyms: CarbaMic acid, N-[4-(trifluoroMethyl)phenyl]-, ethyl ester
• CAS NO: 23794-73-2
• Molecular Formula: C₁₀H₁₀F₃NO₂
• Molecular Weight: 233.1871096
• Mol File: 23794-73-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: CarbaMic acid, N-[4-(trifluoroMethyl)phenyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CarbaMic acid, N-[4-(trifluoroMethyl)phenyl]-, ethyl ester(23794-73-2)
• EPA Substance Registry System: CarbaMic acid, N-[4-(trifluoroMethyl)phenyl]-, ethyl ester(23794-73-2)

Safety Data

• Hazardous Substances Data: 23794-73-2(Hazardous Substances Data)

Usage

General Description

Carbamic Acid, N-[4-(trifluoromethyl)phenyl]-, ethyl ester is a chemical compound that belongs to the class of compounds known as carbamic acid esters. It typically takes the form of a solid, crystalline substance that varies from clear, white to off-white in color. It has unique chemical properties including a trifluoromethyl group and an ethyl ester functional group. The trifluoromethyl group generally enhances the compound's stability, while the ethyl ester group is known for its role in facilitating reactions. This chemical is commonly used in various industrial and manufacturing scenarios, including the production of polymers, foams, and other related materials.

Upstream product

• 101-99-5 N-carboethoxyaniline 
• 2926-29-6 Langlois reagent 
• 455-14-1 4-trifluoromethylphenylamine 
• 541-41-3 chloroformic acid ethyl ester 
• 64-17-5 ethanol 
• 1548-13-6 p-trifluoromethyl-phenylisocyanate 

Downstream Products

• 22864-65-9 N-methyl-4-(trifluoromethyl)aniline 
• 35367-31-8 N-(4-Trifluoromethylphenyl)-N'-(2,6-difluoro-benzoyl)-urea 

Relevant articles and documents

Photoredox-Catalyst-Enabled para-Selective Trifluoromethylation of tert-Butyl Arylcarbamates

The direct incorporation of a trifluoromethyl group on an aromatic ring using a radical pathway has been extensively investigated. However, the direct highly para-selective C?H trifluoromethylation of a class of arenes has not been achieved. In this study, we report a light-promoted 4,5-dichlorofluorescein (DCFS)-enabled para-selective C?H trifluoromethylation of arylcarbamates using Langlois reagent. The preliminary mechanistic study revealed that the activated organic photocatalyst coordinated with the arylcarbamate led to para-selective C?H trifluoromethylation. Ten-gram scale reaction performs well highlighting the synthetic importance of this new protocol.

Synthesis of 4-substituted-1,2-dihydroquinolines by means of gold-catalyzed intramolecular hydroarylation reaction of n-ethoxycarbonyl-n-propargylanilines

An alternative Au(I)-catalyzed synthetic route to functionalized 1,2-dihydroquinolines is reported. This novel approach is based on the use of N-ethoxycarbonyl protected-Npropargylanilines as building blocks that rapidly undergo the IMHA reaction affording the 6-endo cyclization product in good to high yields. In the presence of N-ethoxycarbonyl-N-propargyl-metasubstituted anilines, the regiodivergent cyclization at the ortho-/para-position is achieved by the means of catalyst fine tuning.

Synthesis and insecticidal evaluation of propesticides of benzoylphenylureas

Two series of benzoylphenylurea derivatives were synthesized as candidate propesticides by a nucleophilic addition reaction between 2,6-difluronbenzoyl isocyanate and N-substitutedaniline. The new compounds were identified by 1H NMR spectroscopy, electron ionization-mass spectrometry, and elemental analyses. The bioactivities of the new compounds were evaluated. All of the propesticides reported here were soluble in most organic solvents, and their hydrophobicities were improved obviously. The result of the bioactivities of the new compounds against Oriental armyworm showed that some of the new compounds are good as compared to diflubenzuron and penfluron.