2381-39-7 Usage
Description
6-METHYLBENZO[A]PYRENE is a polycyclic aromatic hydrocarbon (PAH) derivative that is known for its endocrine-disrupting properties. It is a significant compound for understanding the effects of PAHs on human health.
Uses
Used in Environmental and Health Research:
6-METHYLBENZO[A]PYRENE is used as a research compound for studying the impact of PAHs and their derivatives on human health. It helps in understanding the mechanisms of endocrine disruption and the potential risks associated with exposure to these chemicals.
Used in Toxicology Studies:
In the field of toxicology, 6-METHYLBENZO[A]PYRENE is used as a model compound to investigate the toxic effects of PAHs. This helps in developing strategies for risk assessment and mitigation of exposure to these harmful substances.
Used in Pharmaceutical Research:
6-METHYLBENZO[A]PYRENE is also utilized in pharmaceutical research as a tool to study the interactions between PAHs and biological systems. This knowledge can be applied to the development of drugs or therapies targeting PAH-induced health issues.
Used in Chemical Industry:
In the chemical industry, 6-METHYLBENZO[A]PYRENE may be used as a starting material or intermediate in the synthesis of various compounds with potential applications in different fields, such as materials science, electronics, or pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 2381-39-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,8 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2381-39:
(6*2)+(5*3)+(4*8)+(3*1)+(2*3)+(1*9)=77
77 % 10 = 7
So 2381-39-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H14/c1-13-16-7-2-3-8-18(16)19-12-10-15-6-4-5-14-9-11-17(13)21(19)20(14)15/h2-12H,1H3
2381-39-7Relevant articles and documents
Radical Cations of Benzopyrene and 6-Substituted Derivatives: Synthesis and Reaction with Nucleophiles
Cremonesi, Paolo,Stack, Douglas E.,Rogan, Eleanor G.,Cavalieri, Ercole L.
, p. 7683 - 7687 (2007/10/02)
Radial cations of benzopyrene (BP) and 6-substituted derivatives were synthesized by two methods: reaction of the hydrocarbon with I2 and AgClO4 in benzene, and reaction of the hydrocarbon with NOBF4 in CH3CN/CH2Cl2.Both the radical cation perchlorates and tetrafluoroborates were stable for prolonged periods of time when stored under argon at subzero temperatures.The radical cations were reacted with nucleophiles of various strengths, namely H2O, AcO(1-) and F(1-), as a means of best characterizing these intermediates, as well as determining their chemical properties.Reaction of BP, 6-FBP, 6-ClBP, and 6-BrBP radical cation perchlorates with H2O produced BP 1,6-, 3,6-, and 6,12-dione, whereas the radical cation derived from 6-CH3BP yielded 6-CH2OHBP.When BP(.1+)ClO4(1-) and 6-FBP(.1+)ClO4(1-) were reacted with NaOAc in H2O/CH3CN (9:1), 6-OAcBP was formed, in addition to the quinones. 6-ClBP(.1+)ClO4(1-) formed a small amount of 1-OAc-6-ClBP and 3-OAc-6-ClBP, in addition to the diones, whereas for 6-BrBP(.1+)ClO4(1-) and 6-CH3BP(.1+)ClO4(1-) the reaction products were BP diones and 6-CH2OHBP, respectively.Reactions conducted under anhydrous conditions, using tetramethylammonium acetate in CH3CN, gave similar results, except that no quinones were formed.These results confirm the reactivity of nucleophiles at the postions of high charge localization in the BP(.1+), i.e.C-6, followed by C-1 and C-3.
RADIATION-INITIATED OXIDATIVE DEGRADATION OF POLYCYCLIC ARENES
Uibopuu, Kh. M.,Gubergritis, M. Ya.,Perin-Roussel, O.,Perin, F.,Jacquignon, P. S.
, p. 2277 - 2285 (2007/10/02)
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