238753-80-5

Basic information

• Product Name: Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-amine
• Synonyms: Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-amine
• CAS NO: 238753-80-5
• Molecular Weight: 177.246
• Mol File: 238753-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-amine(238753-80-5)
• EPA Substance Registry System: Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-amine(238753-80-5)

Safety Data

• Hazardous Substances Data: 238753-80-5(Hazardous Substances Data)

Upstream product

• 169057-29-8 (R)-1-(oxiran-2-yl)-2-phenylethanone 
• 74-89-5 methylamine 

Downstream Products

• 238753-81-6 Methyl-((S)-1-(S)-oxiranyl-2-phenyl-ethyl)-carbamic acid tert-butyl ester 
• 238753-83-8 [1-benzyl-2-(tert-butyl-dimethyl-silanyloxy)-pent-4-enyl]-methyl-carbamic acid tert-butyl ester 
• 238753-82-7 ((1S,2R)-1-Benzyl-2-methoxymethoxy-pent-4-enyl)-methyl-carbamic acid tert-butyl ester 
• 173204-72-3 (2S,3R)-2-[N-(t-butyloxycarbonyl)-N-methylamino]-1-phenylhex-5-en-3-ol 

Relevant articles and documents

Total synthesis of the multidrug-resistance reversing agent hapalosin

Hapalosin, a new reversing MDR agent, has been synthesized by macrolactamisation of a linear precursor 2 derived from the coupling of a β-hydroxy γ-aminoacid 3 and two hydroxy-esters 4 and 5. The aminoacid 3 was stereoselectively obtained by opening of an anti β-aminoepoxide while the 3-hydroxyacid 4 was prepared by condensation of a lithium compound with (R)-2-phenyl-propanal followed by oxidation of the phenyl group.