23889-85-2

Basic information

• Product Name: 1-Phenyl-4-iodopyrazole
• Synonyms: 1-Phenyl-4-iodopyrazole;4-Iodo-1-phenyl-1H-pyrazole
• CAS NO: 23889-85-2
• Molecular Formula: C₉H₇IN₂
• Molecular Weight: 270.07
• Mol File: 23889-85-2.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 320.5±15.0 °C(Predicted)
• Appearance: /
• Density: 1.75±0.1 g/cm3(Predicted)
• Refractive Index: 1.688
• Storage Temp.: 2-8°C(protect from light)
• PKA: -1.01±0.10(Predicted)
• CAS DataBase Reference: 1-Phenyl-4-iodopyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-4-iodopyrazole(23889-85-2)
• EPA Substance Registry System: 1-Phenyl-4-iodopyrazole(23889-85-2)

Safety Data

• Hazardous Substances Data: 23889-85-2(Hazardous Substances Data)

Usage

General Description

1-Phenyl-4-iodopyrazole is a chemical compound with the molecular formula C9H6IN2. It is a derivative of pyrazole and contains a phenyl group and an iodine atom attached to the pyrazole ring. 1-Phenyl-4-iodopyrazole is commonly used in organic chemistry as a building block for the synthesis of various pharmaceuticals and agrochemicals. It has also been studied for its potential biological activities, such as its use as an inhibitor of certain enzymes and receptors. The presence of the iodine atom in 1-Phenyl-4-iodopyrazole makes it a useful reagent for various chemical reactions, including nucleophilic substitution and cross-coupling reactions in organic synthesis. Overall, 1-Phenyl-4-iodopyrazole is a versatile chemical with important applications in both research and industry.

InChI:InChI=1/C9H7IN2/c10-8-6-11-12(7-8)9-4-2-1-3-5-9/h1-7H

Upstream product

• 1126-00-7 1-phenylpyrazole 
• 288-13-1 NH-pyrazole 
• 273-53-0 benzoxazole 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 3469-69-0 4-iodopyrazole 
• 98-80-6 phenylboronic acid 
• 62-53-3 aniline 
• 141998-88-1 4-tributylstannyl-1-phenylpyrazole 

Downstream Products

• 1002334-12-4 1-phenyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 
• 18830-03-0 1,1'-diphenyl-1H,1'H-4,4'-bipyrazole 
• 763138-83-6 1,1'-bis-(toluene-4-sulfonyl)-1H,1'H-[3,3']biindolyl 
• 709-04-6 1-phenyl-1H-pyrazole-4-carbonitrile 
• 3994-48-7 4-nitro-1-phenylyrazole 
• 15132-01-1 1,4-diphenyl-1H-pyrazole 
• 1393880-13-1 C₁₆H₁₃FN₂O 
• 1393880-12-0 C₁₅H₁₀ClFN₂ 
• 1393880-17-5 C₂₁H₁₅N₃ 
• 1393880-11-9 C₁₆H₁₁F₃N₂ 

Relevant articles and documents

Mild regioselective iodination of pyrazoles using n-butyltriphenylphosphonium peroxodisulfate

A practical, efficient and inexpensive method of synthesis of iodopyrazoles by the reaction of pyrazoles with iodine using n-butyltriphenylphosphonium peroxodisulfate as an oxidant at room temperature is reported. The use of n-butyltriphenylphosphonium peroxodisulfate is feasible due to its easy preparation and handling, high stability and activity.

TEMPO-mediated C-H amination of benzoxazoles with N-heterocycles

The direct amination of benzoxazoles at C2 using N-heterocycles as nitrogen sources has been developed for the first time. Several kinds of inexpensive oxidants and also electricity were effective for this transformation in the presence of 2,2,6,6- tetram

Disulfide-Catalyzed Iodination of Electron-Rich Aromatic Compounds

Herein, a disulfide-catalyzed electrophilic iodination of aromatic compounds using 1,3-diiodo-5,5-dimethylhydantoin (DIH) has been developed. The disulfide activates DIH as a Lewis base to promote the iodination reaction in acetonitrile under mild conditions. This system is applicable to a wide range of electron-rich aromatic compounds, including acetanilide, anisole, imidazole, and pyrazole derivatives.