23891-96-5

Basic information

• Product Name: (2,2-DIMETHYLPROPANOYL)AMINO]ACETIC ACID
• Synonyms: 2-(pivalamido)acetic acid
• CAS NO: 23891-96-5
• Molecular Formula: C₇H₁₃NO₃
• Molecular Weight: 159.184
• Mol File: 23891-96-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: 134-135 °C
• Boiling Point: 362.2°C at 760 mmHg
• Flash Point: 172.8°C
• Appearance: /
• Density: 1.100±0.06 g/cm3(Predicted)
• Vapor Pressure: 3.14E-06mmHg at 25°C
• Storage Temp.: 2-8°C
• PKA: 3.62±0.10(Predicted)
• CAS DataBase Reference: (2,2-DIMETHYLPROPANOYL)AMINO]ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2-DIMETHYLPROPANOYL)AMINO]ACETIC ACID(23891-96-5)
• EPA Substance Registry System: (2,2-DIMETHYLPROPANOYL)AMINO]ACETIC ACID(23891-96-5)

Safety Data

• Hazardous Substances Data: 23891-96-5(Hazardous Substances Data)

Usage

Uses

N-Pivaloylglycine is used in the biological study between dogs and rats. In a high dose toxicity study of pivalic acid (PA), PA caused skeletal muscle disorder in dog, and a significant increase of pivaloyl carnitine (PC) was observed in canine muscle, but not in rat muscle.

InChI:InChI=1/C7H13NO3/c1-7(2,3)6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)/p-1

Upstream product

• 5680-79-5 glycine ethyl ester hydrochloride 
• 3282-30-2 pivaloyl chloride 
• 42014-50-6 succinimidyl 2,2-dimethylpropionate 
• 56-40-6 glycine 

Downstream Products

• 155477-86-4 N-pivaloylglycine (-)-menthyl ester 
• 136745-11-4 Boc-Gly-Phe-OMe 
• 1019770-58-1 N-pivaloylaminomethyltriphenylphosphonium tetrafluoroborate 
• 1439361-26-8 C₁₃H₁₉NOS 
• 26209-46-1 ethyl N-(2,2-dimethyl-1-oxopropyl)glycinate 
• 176793-33-2 2-tert-Butyl-4-(triphenyl-λ⁵-phosphanylidene)-4H-oxazol-5-one 
• 848150-57-2 (Z)-3-(3,4-dimethoxyphenyl)-N-methyl-2-pivaloylamino-2-propenamide 

Relevant articles and documents

Scorpio-Ligand: Synthesis of Biphenyl-Dihydroazepine Phosphoramidite Ligands for Asymmetric Hydrogenation

A novel dihydroazepine-bridged BIPHEP phosphoramidite ligand with an amino acid moiety in the backbone was synthesized and evaluated in the Rh-catalyzed asymmetric hydrogenation. The scorpion tail-like amino acid backbone is capable of hydrogen bond forma

Pd(II)-Catalyzed [4 + 2] Heterocyclization Sequence for Polyheterocycle Generation

A new Pd(II)-catalyzed cascade sequence for the formation of polyheterocycles, from simple starting materials, is reported. The sequence is applicable to both indole and pyrrole substrates, and a range of substituents are tolerated. The reaction is thought to proceed by a Pd(II)-catalyzed C-H activated Heck reaction followed by a second Pd(II)-catalyzed aza-Wacker reaction with two Cu(II)-mediated Pd(0) turnovers per sequence. The sequence can be considered a formal [4 + 2] heterocyclization.

PYRONE COMPOUND AND ITS USE FOR PEST CONTROL

A pyrone compound represented by formula (1) has an excellent controlling effect on pests. Since the compound of formula (1) has a controlling activity on pests, the compound is useful as an active ingredient of a pest control agent.