2390-74-1

Basic information

• Product Name: GLYCYL-L-TRYPTOPHAN
• Synonyms: glycyltryptophan hydrate;L-Tryptophan, N-glycyl- (9CI);Gly-Trp-OH≥ 99% (HPLC);Glycyltryptophan;l-Glycyltryptophan;L-Tryptophan, N-glycyl-;N-(Aminoacetyl)tryptophan;Na-glycyl-l-tryptophan
• CAS NO: 2390-74-1
• Molecular Formula: C₁₃H₁₅N₃O₃
• Molecular Weight: 261.28
• EINECS: 219-235-7
• Product Categories: Biochemistry;Indoles;Oligopeptides;Peptide Synthesis;Tryptophans
• Mol File: 2390-74-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 621.8°Cat760mmHg
• Flash Point: 329.9°C
• Appearance: /
• Density: 1.383g/cm³
• Refractive Index: 1.696
• Storage Temp.: -15°C
• Solubility: almost transparency in 5mol/L HCl
• PKA: 3.15±0.10(Predicted)
• CAS DataBase Reference: GLYCYL-L-TRYPTOPHAN(CAS DataBase Reference)
• NIST Chemistry Reference: GLYCYL-L-TRYPTOPHAN(2390-74-1)
• EPA Substance Registry System: GLYCYL-L-TRYPTOPHAN(2390-74-1)

Safety Data

• Hazardous Substances Data: 2390-74-1(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Definition

ChEBI: A dipeptide formed from glycine and L-tryptophan residues.

InChI:InChI=1/C13H15N3O3/c14-6-11(17)13(15,12(18)19)5-8-7-16-10-4-2-1-3-9(8)10/h1-4,7,16H,5-6,14-15H2,(H,18,19)

Upstream product

• 86961-48-0 3-[2-Benzyloxycarbonyl-2-(2-tert-butoxycarbonylamino-acetylamino)-ethyl]-indole-1-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 86961-49-1 3-[2-(2-Amino-acetylamino)-2-carboxy-ethyl]-indole-1-carboxylic acid 2,2,2-trichloro-ethyl ester 
• 56-40-6 glycine 
• 73-22-3 L-Tryptophan 
• 885119-86-8 N-[2-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-L-tryptophan 

Relevant articles and documents

Identification of novel L-amino acid α-ligases through hidden markov model-based profile analysis

L-Amino acid α-ligase (Lal), catalyzing the formation of α-dipeptides from unprotected l-amino acids in an ATP-dependent manner, is used in cost-effective fermentative production of dipeptides. We searched for novel Lals by in silico screening using Hidden Markov Model-based profile analysis, and identified five novel Lals that showed low similarity and different substrate specificity from known Lals.

PROTECTION OF THE TRYPTOPHAN INDOLE RING IN PEPTIDE SYNTHESIS. USE OF A NEW DERIVATIVE, Nin-2,2,2-TRICHLOROETHOXYCARBONYLTRYPTOPHAN

The 2,2,2-trichloroethoxycarbonyl (Troc) group attached at the Nin function of tryptophan by acylation with Troc-Cl in the presence of a catalytic amount of tetra-n-butylammonium hydrogensulfate can be quantitatively removed either by cadmium dust in acetic acid or under basic conditions, e. g., hydrazine hydrate and NaOH, but is resistant to strong acidic conditions.