23943-58-0

Basic information

• Product Name: (R)-N-(1-naphthalen-1-ylethyl)-p,p-diphenylphosphinc amide
• Synonyms: (R)-N-(1-naphthalen-1-ylethyl)-p,p-diphenylphosphinc amide
• CAS NO: 23943-58-0
• Molecular Weight: 371.419
• Mol File: 23943-58-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (R)-N-(1-naphthalen-1-ylethyl)-p,p-diphenylphosphinc amide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-N-(1-naphthalen-1-ylethyl)-p,p-diphenylphosphinc amide(23943-58-0)
• EPA Substance Registry System: (R)-N-(1-naphthalen-1-ylethyl)-p,p-diphenylphosphinc amide(23943-58-0)

Safety Data

• Hazardous Substances Data: 23943-58-0(Hazardous Substances Data)

Upstream product

• 1956-40-7 1-(1-naphthalenyl)ethanone oxime 
• 941-98-0 1'-naphthacetophenone 
• 82572-09-6 C₂₄H₂₀NOP 
• 1079-66-9 chloro-diphenylphosphine 
• 942066-01-5 N-[(E)-1-(1-naphthyl)ethylidene]diphenylphosphinic amide 

Downstream Products

• 3886-70-2 (R)-1-(1-Naphthyl)ethylamine 

Relevant articles and documents

Asymmetric reduction method of nitrogen-phosphonyl protected imine

The invention discloses an asymmetric reduction method of nitrogen phosphonyl protective imine. The nitrogen phosphonyl protective imine is reduced into chiral amine in a hydrogen atmosphere under theaction of a metal catalyst and alkali, and the metal catalyst is prepared from a metal iridium complex and a nitrogen-phosphorus chiral ligand. The method provided by the invention has the characteristics of high enantioselectivity, high yield and high conversion number (TON). The method can be used for synthesizing various substituted chiral amines, can be used as an important intermediate for preparing various medicines, and has important significance for industrial production of medicines.

Asymmetric transfer hydrogenation of ketimines using well-defined iron(II)-based precatalysts containing a PNNP ligand

Well-defined iron(II)-based complexes containing PNNP ligands catalyze a highly enantioselective reduction of N-(diphenylphosphinoyl)- and N-(p-tolylsulphonyl)-ketimines. Under mild conditions and low catalyst loading, the ketimines are successfully reduced to the corresponding amines in enantiomeric excess ranging from 94 to 99%.

Asymmetric Reduction of Phosphinyl Imines with Hydride Reagents. Enantioselective Synthesis of Chiral Primary Amines

Prochiral diphenylphosphinyl imines are asymmetrically reduced by chiral hydride reagents to chiral diphenylphosphinylamines.For dialkyl examples, the enantioselectivities obtained are the highest thus far for hydride reductions of imine derivatives.