23964-58-1 Usage
Description
Articaine, also known as 4-methyl-3-(2-propylaminopropionamido) thiophene-2-carboxylic acid methyl ester hydrochloride, is a unique amide-based local anesthetic that has been widely used in dentistry since its approval by the U.S. FDA in the year 2000. It is characterized by its quick onset and short duration of action, which is attributed to its rapid hydrolysis. Articaine's molecular structure contains a thiophene ring instead of a benzene ring and a carbomethoxy group, making it more lipophilic and easier to cross lipoidal membranes. Its local anesthetic potency is approximately 1.5 times that of lidocaine.
Uses
Used in Dentistry:
Articaine is used as a local anesthetic for infiltration anesthesia in dental procedures due to its quick onset and short duration of action. It is available as a 4% solution with adrenaline, making it the drug of choice for dentistry.
Used in Regional Anesthesia:
Articaine is used as a short-acting local anesthetic for regional anesthesia in day-case settings such as arthroscopy, hand, foot surgery, and other minor surgical procedures. Its rapid hydrolysis and metabolism by plasma cholinesterases contribute to its shorter duration of action compared to other local anesthetics like mepivacaine, lidocaine, or prilocaine, making it a much safer drug for regional anesthesia.
Therapeutic Function
Local anesthetic
Check Digit Verification of cas no
The CAS Registry Mumber 23964-58-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,6 and 4 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 23964-58:
(7*2)+(6*3)+(5*9)+(4*6)+(3*4)+(2*5)+(1*8)=131
131 % 10 = 1
So 23964-58-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H20N2O3S/c1-5-6-14-9(3)12(16)15-10-8(2)7-19-11(10)13(17)18-4/h7,9,14H,5-6H2,1-4H3,(H,15,16)
