2398-75-6Relevant articles and documents
A general and practical Ni-catalyzed C-H perfluoroalkylation of (hetero)arenes
Zhang, Shaoke,Rotta-Loria, Nicolas,Weniger, Florian,Rabeah, Jabor,Neumann, Helfried,Taeschler, Christoph,Beller, Matthias
supporting information, p. 6723 - 6726 (2019/06/17)
A direct perfluoroalkylation of (hetero)arenes using the air- and moisture-stable complex (dppf)Ni(o-tol)Cl was developed (23 examples). The novel procedure allows for the synthesis of various fluorinated products and tolerates sensitive functional groups including aldehydes, free amino groups and several heterocycles.
Copper-mediated aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides at room temperature
Qi, Qingqing,Shen, Qilong,Lu, Long
supporting information; experimental part, p. 6548 - 6551 (2012/06/04)
A Cu-mediated ligandless aerobic fluoroalkylation of arylboronic acids under mild conditions is described for the first time. The reaction tolerates a wide range of functional groups, allowing for further transformation. Mechanistic studies suggest that [RfCu] is the active Cu species that forms the desired perfluoroalkylarenes and that [RfCu] is generated from [PhCu] by either an oxidative addition/reductive elimination mechanism or nucleophilic substitution via a halogen "ate" intermediate.
Fluorous-tagged indolylboron for the diversity-oriented synthesis of biologically-attractive bisindole derivatives
Kasahara, Takahiro,Kondo, Yoshinori
, p. 891 - 893 (2008/02/08)
The diversity-oriented synthesis of bisindole derivatives to construct concise libraries using consecutive cross-coupling reactions and prepare new sulfonamide type fluorous protecting groups is presented. The Royal Society of Chemistry 2006.
