24079-79-6

Basic information

• Product Name: 1-Cyclohexene-1-carboxylic acid, 3-oxo-
• CAS NO: 24079-79-6
• Molecular Formula: C7H8O3
• Molecular Weight: 140.139
• Mol File: 24079-79-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexene-1-carboxylic acid, 3-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexene-1-carboxylic acid, 3-oxo-(24079-79-6)
• EPA Substance Registry System: 1-Cyclohexene-1-carboxylic acid, 3-oxo-(24079-79-6)

Safety Data

• Hazardous Substances Data: 24079-79-6(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 201230-82-2 carbon monoxide 
• 77708-66-8 3-oxocyclohex-1-en-1-yl 4-methylbenzenesulfonate 
• 5682-75-7 3-chloro-2-cyclohexenone 
• 636-82-8 cyclohexene-1-carboxylic acid 
• 1617-22-7 cyclohex-1-enecarboxylic acid ethyl ester 
• 18448-47-0 methyl cyclohex-1-ene-1-carboxylate 
• 56671-81-9 3-bromo-2-cyclohexen-1-one 
• 54396-74-6 3-oxocyclohex-1-ene-1-carboxylic acid methyl ester 
• 124-38-9 carbon dioxide 
• 81036-84-2 3-bromocyclohex-2-en-1-one ethylene ketal 
• 25017-79-2 ethyl 3-oxocyclohex-1-ene-1-carboxylate 
• 25017-78-1 3-cyano-2-cyclohexenone 

Downstream Products

• 188540-74-1 (1S)-1-(1-allyloxycarbonyl)ethyl 3-oxocyclohex-1-enecarboxylate 
• 188540-76-3 (1S)-[1-(1-allyloxycarbonyl)-1-(1S)-ethyloxycarbonyl]ethyl 3-oxocyclohex-1-enecarboxylate 
• 188540-79-6 (1R)-1-(2-allyloxycarbonyl-1-methyl)ethyl 3-oxocyclohex-1-enecarboxylate 
• 668452-70-8 (-)-(1R,2S,5R)-5-methyl-2-[1-methyl-1-(2-naphthyl)ethyl]cyclohexyl cyclohexen-3-one-1-carboxylate 
• 1252572-15-8 (-)-(1R,2S,5R)-2-[2-(4-isopropylphenyl)propan-2-yl]-5-methylcyclohexyl 3-oxo-1-cyclohexenecarboxylate 
• 54396-74-6 3-oxocyclohex-1-ene-1-carboxylic acid methyl ester 
• 21531-46-4 (+)-(S)-3-oxo-1-cylcohexanecarboxylic acid 

Relevant articles and documents

PROCESS FOR PREPARING CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACID COMPOUNDS

Improved methods and intermediates thereof for preparing carbamoyloxy methyl triazole cyclohexyl acid compounds are described. These compounds are useful as LPA antagonists. Formula (I).

Allylic oxidations catalyzed by dirhodium caprolactamate via aqueous tert-butyl hydroperoxide: The role of the tert-butylperoxy radical

Dirhodium(II) caprolactamate exhibits optimal efficiency for the production of the tert-butylperoxy radical, which is a selective reagent for hydrogen atom abstraction. These oxidation reactions occur with aqueous tert-butyl hydroperoxide (TBHP) without rapid hydrolysis of the caprolactamate ligands on dirhodium. Allylic oxidations of enones yield the corresponding enedione in moderate to high yields, and applications include allylic oxidations of steroidal enones. Although methylene oxidation to a ketone is more effective, methyl oxidation to a carboxylic acid can also be achieved. The superior efficiency of dirhodium(II) caprolactamate as a catalyst for allylic oxidations by TBHP (mol % of catalyst, % conversion) is described in comparative studies with other metal catalysts that are also reported to be effective for allylic oxidations. That different catalysts produce essentially the same mixture of products with the same relative yields suggests that the catalyst is not involved in product-forming steps. Mechanistic implications arising from studies of allylic oxidation with enones provide new insights into factors that control product formation. A previously undisclosed disproportionation pathway, catalyzed by the tert-butoxy radical, of mixed peroxides for the formation of ketone products via allylic oxidation has been uncovered.

SPECIFITY OF E. COLI SHIKIMATE DEHYDROGENASE TOWARDS ANALOGUES OF 3-DEHYDROSHIKIMIC ACID

Analogues of 3-dehydroshikimic acid which lack the C-4 and C-5 hydroxyl groups have been synthesised and assayed as substrates for shikimate dehydrogenase.The presence of the C-4 hydroxyl group is found to be very important for specificity, whereas the C-5 hydroxyl group is not.The enzyme exhibits enantioselectivity at C-1 and C-4 of the racemic substrate analogues.