241149-78-0

Basic information

• Product Name: Octanoic acid, 4-hydroxy-7-methyl-2-methylene-5-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (4S,5S)-
• CAS NO: 241149-78-0
• Molecular Formula: C19H27NO5
• Molecular Weight: 349.427
• Mol File: 241149-78-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Octanoic acid, 4-hydroxy-7-methyl-2-methylene-5-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (4S,5S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Octanoic acid, 4-hydroxy-7-methyl-2-methylene-5-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (4S,5S)-(241149-78-0)
• EPA Substance Registry System: Octanoic acid, 4-hydroxy-7-methyl-2-methylene-5-[[(phenylmethoxy)carbonyl]amino]-, methyl ester, (4S,5S)-(241149-78-0)

Safety Data

• Hazardous Substances Data: 241149-78-0(Hazardous Substances Data)

Upstream product

• 6216-61-1 (S)-(-)-N-(benzyloxycarbonyl)leucinol 
• 4224-69-5 methyl 2-(bromomethyl)propenoate 
• 70853-26-8 N-carbobenzoxy-L-leucinal 

Downstream Products

• 239135-75-2 (5S,1'S)-5-[1-(benzyloxycarbonylamino)-3-methylbutyl]-3-methylenedihydro-2(3H)-furanone 

Relevant articles and documents

Synthetic studies towards anti-SARS agents: Application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate

AG7088 was identified as a good starting point for modification, leading to an efficient and bio-available inhibitor for the SARS coronavirus main proteinase (SARS-CoV Mpro). Synthesis of intermediate 1 and analogues proceeded via a highly diastereoselective indium-mediated allylation of α-aminoaldehydes.