241154-04-1

Basic information

• Product Name: 5-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan
• Synonyms: 3-(Fur-2-yl)-2-(trifluoromethyl)propanoic acid;5-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan;2-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan, 3-(Fur-2-yl)-2-(trifluoromethyl)propionic acid
• CAS NO: 241154-04-1
• Molecular Formula: C8H7F3O3
• Molecular Weight: 208.1345896
• Mol File: 241154-04-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 238.7±40.0 °C(Predicted)
• Appearance: /
• Density: 1.392±0.06 g/cm3(Predicted)
• PKA: 2.96±0.11(Predicted)
• CAS DataBase Reference: 5-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan(241154-04-1)
• EPA Substance Registry System: 5-(2-Carboxy-3,3,3-trifluoroprop-1-yl)furan(241154-04-1)

Safety Data

• Hazardous Substances Data: 241154-04-1(Hazardous Substances Data)

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 98-01-1 furfural 

Relevant articles and documents

Catalytic asymmetric hydrogenation of α-CF3- or β-CF3-Substituted acrylic acids using Rhodium(I) complexes with a combination of chiral and achiral ligands

Only the mixture works! Acrylic acid derivatives with CF3 substituents in α or β position were efficiently hydrogenated in the presence of a RhI complex with a chiral secondary phosphine oxide (SPO; see scheme) and an achiral Ph3P as ligands. The corresponding propanoic acid derivatives were obtained with generally high conversion (>99 %) and high enantioselectivity (92->99 %). Copyright