2412-49-9Relevant articles and documents
Me3SiCl-promoted intramolecular cyclization of aromatic compounds tethered with N,O-acetals leading to the facile preparation of 1,4-benzodiazepine skeletons
Sakai, Norio,Watanabe, Akimasa,Ikeda, Reiko,Nakaike, Yumi,Konakahara, Takeo
experimental part, p. 8837 - 8845 (2010/11/19)
The Me3SiCl-promoted intramolecular aminomethylation of a novel type of N,O-acetals, which were prepared via a facile three-step synthesis from N-alkylaniline derivatives and N-alkyl-2-oxazolidinones that leads to the production of pharmaceutically useful 1,4-benzodiazepine skeletons with a variety of functional groups is described. This method was successfully applied to the facile preparation of both tricyclic benzodiazepine derivatives and a 1,4-benzoxazepine derivative via 7-exo-trig cyclization.
Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. IV. Modification of the phenylpiperazino moiety of 2-(phenylpiperazinoalkoxyphenyl)thiazolidine-3- carbothioamides and the corresponding carboxamides
Nate,Watanabe,Matsuki,Inoue,Ohtsuka,Sekine,Oda,Honma,Ishida,Kanno
, p. 2825 - 2839 (2007/10/02)
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