24165-63-7

Basic information

• Product Name: 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97
• Synonyms: 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97;1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97%
• CAS NO: 24165-63-7
• Molecular Formula: C₁₁H₁₄O
• Molecular Weight: 162.23
• Product Categories: Acyclic;Alkenes;Organic Building Blocks;Building Blocks;Chemical Synthesis;Organic Building Blocks
• Mol File: 24165-63-7.mol
• Article Data: 196

Chemical Properties

• Boiling Point: 253 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 0.983 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00488mmHg at 25°C
• Refractive Index: n20/D 1.5270(lit.)
• PKA: 14.36±0.20(Predicted)
• CAS DataBase Reference: 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97(24165-63-7)
• EPA Substance Registry System: 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97(24165-63-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 24165-63-7(Hazardous Substances Data)

Usage

Description

1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97, also known as 1-p-tolyl-but-3-en-1-ol, is a homoallylic alcohol derivative with a unique chemical structure that allows for various applications in different industries. It can be synthesized through the allylation of 4-methylbenzaldehyde using potassium allyltrifluoroborate in the presence of 18-crown-6. 1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97 has the ability to undergo Prins cyclization in the presence of cellulose-sulfonic acid, forming the corresponding tetrahydropyran-4-ol.

Uses

Used in Chemical Synthesis:
1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97 is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable building block in the development of new molecules with potential applications in pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Flavor and Fragrance Industry:
1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97 is used as a component in the creation of unique and complex fragrances and flavors. Its distinct chemical structure contributes to the overall sensory profile of the final product, making it an important ingredient in the development of new and innovative scents and tastes.
Used in Pharmaceutical Industry:
1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97 is used as a starting material for the development of new pharmaceutical compounds. Its versatile chemical structure allows for the creation of novel drug candidates with potential therapeutic applications in various medical fields.
Used in Material Science:
1-(4-METHYLPHENYL)-3-BUTEN-1-OL 97 can be utilized in the development of new materials with unique properties. Its chemical structure can be modified to create new polymers, coatings, and other materials with specific characteristics, such as improved strength, durability, or chemical resistance.

InChI:InChI=1/C11H14O/c1-3-4-11(12)10-7-5-9(2)6-8-10/h3,5-8,11-12H,1,4H2,2H3

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 627-15-6 1,3-dibromopropene 
• 24850-33-7 allyltributylstanane 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 132017-23-3 C₁₅H₃₂BrSb 
• 762-73-2 trimethyl(allyl)stannane 
• 114571-77-6 triethylammonium bis(catecholato)(3-methyl-2-butenyl)siliconate 
• 114612-18-9 triethylammonium bis(pyrocatecholato)allylsilicate 
• 2551-83-9 allyltrimethoxysilane 
• 2550-04-1 allyltriethoxysilane 
• 556-56-9 allyl iodid 
• 106-95-6 allyl bromide 
• 71104-78-4 4-acetoxy-4-(p-methylphenyl)-1-butene 
• 14593-43-2 benzyl allyl ether 

Downstream Products

• 1027300-03-3 C₁₆H₂₄OSi 
• 3837-95-4 (E)-1-(4-methylphenyl)-2-buten-1-one 
• 1453859-74-9 (Z)-1-p-tolylbut-2-en-1-one 
• 4160-52-5 1-(4-methylphenyl)butan-1-one 
• 1335143-76-4 C₁₄H₁₆O₂ 
• 1332831-65-8 6-p-tolyl-5,6-dihydro-2H-pyran-2-one 
• 1280224-70-5 (E)-4-methyl-N-(4-p-tolylbut-3-en-2-yl)benzenesulfonamide 
• 1260869-61-1 tert-butyl (E)-5-hydroxy-5-(4-methylphenyl)pent-2-enyl carbonate 
• 1251857-73-4 (E)-1-methyl-4-((4-(p-tolyl)but-3-en-2-yl)sulfonyl)benzene 
• 1242077-04-8 (E)-4-phenyl-1-(4-p-tolylbut-3-en-2-yl)-1H-1,2,3-triazole 
• 1242076-95-4 (E)-1-(3-azidobut-1-enyl)-4-methylbenzene 
• 1210066-97-9 (E)-4-hydroxy-4-p-tolylbut-2-enyl pivalate 
• 1210066-95-7 C₁₄H₁₈O₃ 
• 104175-13-5 4-(4-methylphenyl)-3-buten-2-ol 

Relevant articles and documents

2,3-Wittig rearrangement by partial reduction of diallyl acetals with SmI2 in acetonitrile

Diallyl acetals undergo reductive cleavage of an allyloxy group by SmI2 to generate α-allyloxy carbanions, which are transformed into homoallyl alcohols by 2,3-Wittig rearrangement.

Visible Light-Promoted Recyclable Carbon Nitride-Catalyzed Dioxygenation of β,γ-Unsaturated Oximes

A visible-light-induced dioxygenation of β,γ-unsaturated oximes for the synthesis of diverse useful isoxazolines bearing a hydroxyl moiety was developed by employing graphitic carbon nitride (g-C3N4) as a heterogeneous photocatalyst under an air atmosphere. Noted that, the eminent advantages of this metal-free protocol include step economy, easy operation, a recyclable photocatalyst, external reductant-/oxidant-free and mild reaction conditions. Additionally, mechanistic studies indicated hydroxyl radical was generated under the photocatalysis of g-C3N4.

Photocatalytic Umpolung Synthesis of Nucleophilic π-Allylcobalt Complexes for Allylation of Aldehydes

The concept of "umpolung"reactivity of π-allylmetal complexes has been developed as a powerful method for the allylation of aldehydes. This paper describes the photocatalytic umpolung strategy for the synthesis of nucleophilic allylcobalt complexes through a single-electron-transfer (SET) process. This strategy enables the metallaphotoredox allylation of carbonyls with allyl acetate using organic N,N-diisopropylethylamine as the terminal reductant bypassing the use of a stoichiometric amount of metals. Ultraviolet-visible spectroscopy was used to monitor the redox changes of cobalt in the reaction.