242129-02-8Relevant articles and documents
Synthesis of 3-phenylpyrazolo[4,3-b]pyridines via a convenient synthesis of 4-amino-3-arylpyrazoles and SAR of corticotropin-releasing factor receptor type-1 antagonists
Wilcoxen, Keith,Huang, Charles Q.,McCarthy, James R.,Grigoriadis, Dimitri E.,Chen, Chen
, p. 3367 - 3370 (2007/10/03)
3-Phenylpyrazolo[4,3-b]pyridines were synthesized via a cyclization of 4-amino-3-phenylpyrazoles 11-13 with ethyl acetoacetate. These compounds were found to be potent CRF1 antagonists. The 2-alkylpyrazolo[4,3-b]pyridines were more polar but le