2424-00-2

Basic information

• Product Name: 2-(Allylamino)Ethanol
• Synonyms: 2-(Allylamino)Ethanol;2-(allylamino)ethanol(WXC04709)
• CAS NO: 2424-00-2
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.15
• Mol File: 2424-00-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 77-80 °C(Press: 1.5 Torr)
• Appearance: /
• Density: 0.9398 g/cm3
• PKA: 14.78±0.10(Predicted)
• CAS DataBase Reference: 2-(Allylamino)Ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Allylamino)Ethanol(2424-00-2)
• EPA Substance Registry System: 2-(Allylamino)Ethanol(2424-00-2)

Safety Data

• Hazardous Substances Data: 2424-00-2(Hazardous Substances Data)

Usage

Type of compound

Amino alcohol

Substituent group

Allyl group attached to the amino group

Usage

Raw material in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals

Industrial application

Solvent in certain industrial processes

Reaction potential

Can undergo hydroxylation, sulfation, and acetylation

Chemical versatility

Useful in a wide range of chemical applications

Chelating properties

Can act as a chelating agent

Metal ion interaction

Capable of forming complexes with metal ions

Importance

Serves as an important building block in the production of various chemicals with diverse applications in different industries.

Upstream product

• 159675-32-8 tert-butyl-(prop-2-en-1-ylamino)-acetate 
• 114947-88-5 allyl-carbamic acid-(2-chloro-ethyl ester) 
• 75-21-8 oxirane 
• 107-11-9 1-amino-2-propene 
• 540-51-2 2-bromoethanol 
• 141-43-5 ethanolamine 
• 106-95-6 allyl bromide 

Downstream Products

• 17719-79-8 (N,N-diallyl)-2-aminoethanol 
• 1352740-89-6 N-allyl-N-(2-iodoethyl)-4-cyanobenzenesulfonamide 
• 1352740-90-9 N-allyl-N-(2-iodoethyl)-4-iodobenzenesulfonamide 
• 1352740-91-0 N-allyl-N-(2-iodoethyl)-2-bromobenzenesulfonamide 
• 1352741-01-5 2-bromophenylsulfonyl-3-methylenepyrrolidine 
• 1352740-92-1 N-allyl-N-(2-iodoethyl)-4-hydroxymethylbenzenesulfonamide 
• 1352741-02-6 4-hydroxymethylphenylsulfonyl-3-methylenepyrrolidine 
• 1352740-94-3 N-allyl-N-(2-iodoethyl)-4-formylbenzenesulfonamide 
• 1352740-99-8 4-cyanophenylsulfonyl-3-methylenepyrrolidine 
• 1352741-00-4 4-iodophenylsulfonyl-3-methylenepyrrolidine 
• 1352741-03-7 4-formylphenylsulfonyl-3-methylenepyrrolidine 
• 86553-34-6 Toluene-4-sulfonic acid 2-[allyl-(toluene-4-sulfonyl)-amino]-ethyl ester 
• 1065075-80-0 benzyl allyl(2-hydroxyethyl)carbamate 

Relevant articles and documents

MACROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF DISEASE

The invention relates to heterocyclic compounds of the formula (I), in which all of the variables are as defined in the specification; capable of modulating the activity of CFTR. The invention further provides a method for manufacturing compounds of the invention, and its therapeutic uses. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including Cystic fibrosis and related disorders.

Synthesis of new 3-substituted 1,3-oxazolidine-2-thiones

Reaction of N-alkylsubstituted ethanolamines with carbon disulfide followed by reaction with benzoyl chloride afforded N-substituted oxazolidine-2-thiones.

Cobalt-catalyzed coupling of alkyl iodides with alkenes: Deprotonation of hydridocobalt enables turnover

Completing the cycle: Cobalt complexes I and II were found to catalyze intramolecular alkyl Heck-type coupling reactions of alkyl iodides to alkenes upon irradiation with visible light in the presence of a tertiary amine base. The use of base is key to the catalytic turnover. The compatibility of the method with a broad range of functional groups opens opportunities for synthesis. Copyright