24243-38-7 Usage
General Description
3-(5-methoxy-2,6-dimethyl-9-oxo-3,4,7,9-tetrahydro-2H-furo[3,4-h]chromen-2-yl)propanoic acid is a synthetic organic compound that falls under the category of furocoumarins. It is a derivative of coumarin and is a potent inhibitor of the enzyme lipoxygenase, which plays a role in inflammation and some cancers. 3-(5-methoxy-2,6-dimethyl-9-oxo-3,4,7,9-tetrahydro-2H-furo[3,4-h]chromen-2-yl)propanoic acid has shown promising results in preclinical studies for its anti-inflammatory and anti-cancer properties. Its chemical structure contains a furanocoumarin ring system with a methoxy group and a propanoic acid moiety. Further research into its potential therapeutic applications is ongoing.
Check Digit Verification of cas no
The CAS Registry Mumber 24243-38-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,2,4 and 3 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24243-38:
(7*2)+(6*4)+(5*2)+(4*4)+(3*3)+(2*3)+(1*8)=87
87 % 10 = 7
So 24243-38-7 is a valid CAS Registry Number.
24243-38-7Relevant articles and documents
Functional characterization of MpaG′, the O-methyltransferase involved in the biosynthesis of mycophenolic acid
Zhang, Wei,Cao, Shaona,Qiu, Li,Qi, Fengxia,Li, Zhong,Yang, Ying,Huang, Shaohua,Bai, Fali,Liu, Changning,Wan, Xiaobo,Li, Shengying
, p. 565 - 569 (2015)
Mycophenolic acid (MPA, 1) is a clinically important immunosuppressant. In this report, a gene cluster mpa′' responsible for the biosynthesis of 1 was identified from Penicillium brevicompactum NRRL 864. The S-adenosyl-L-methionine-dependent (SAM-dependent) O-methyltransferase encoded by the mpaG′ gene was functionally and kinetically characterized in vitro. MpaG′ catalyzes the methylation of demethylmycophenolic acid (DMMPA, 6) to form 1. It also showed significant substrate flexibility by methylating two structural derivatives of 6 prepared by organic synthesis.
